医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
18期
52-53
,共2页
PCT%HBV-ACLF%CRP%细菌
PCT%HBV-ACLF%CRP%細菌
PCT%HBV-ACLF%CRP%세균
PCT%HBV-ACLF%CRP%bacterial
目的探讨PCT对HBV-ACLF并发细菌感染的早期诊断及抗菌治疗的作用。方法选取2011年1月-2013年1月在我院医院感染科住院的98例慢性HBV-ACLF作为研究对象，以患者细菌培养结果分为细菌感染组以及非细菌感染组，并进行PCT以及CRP的测定，同时观察PCT阳性的细菌感染患者经过抗菌治疗后的PCT情况。结果细菌感染组患者的PCT阳性率明显高于非细菌感染组（91.94% vs19.44%，χ2=52.824，p=0.000），而细菌感染组患者的CRP阳性率与非细菌感染组比较无统计学差异（83.87% vs 66.67%，χ2=3.872，p=0.049）；细菌感染组中57例患者在抗感染治疗前PCT的阳性率是100%(57/57)，经抗菌药物治疗后PCT阳性率显著下降，为14.03%（8/57）。结论血清PCT检测对HBV-ACLF并发细菌感染的早期诊断有重要价值，并能指导抗菌药物进行抗菌治疗。
目的探討PCT對HBV-ACLF併髮細菌感染的早期診斷及抗菌治療的作用。方法選取2011年1月-2013年1月在我院醫院感染科住院的98例慢性HBV-ACLF作為研究對象，以患者細菌培養結果分為細菌感染組以及非細菌感染組，併進行PCT以及CRP的測定，同時觀察PCT暘性的細菌感染患者經過抗菌治療後的PCT情況。結果細菌感染組患者的PCT暘性率明顯高于非細菌感染組（91.94% vs19.44%，χ2=52.824，p=0.000），而細菌感染組患者的CRP暘性率與非細菌感染組比較無統計學差異（83.87% vs 66.67%，χ2=3.872，p=0.049）；細菌感染組中57例患者在抗感染治療前PCT的暘性率是100%(57/57)，經抗菌藥物治療後PCT暘性率顯著下降，為14.03%（8/57）。結論血清PCT檢測對HBV-ACLF併髮細菌感染的早期診斷有重要價值，併能指導抗菌藥物進行抗菌治療。
목적탐토PCT대HBV-ACLF병발세균감염적조기진단급항균치료적작용。방법선취2011년1월-2013년1월재아원의원감염과주원적98례만성HBV-ACLF작위연구대상，이환자세균배양결과분위세균감염조이급비세균감염조，병진행PCT이급CRP적측정，동시관찰PCT양성적세균감염환자경과항균치료후적PCT정황。결과세균감염조환자적PCT양성솔명현고우비세균감염조（91.94% vs19.44%，χ2=52.824，p=0.000），이세균감염조환자적CRP양성솔여비세균감염조비교무통계학차이（83.87% vs 66.67%，χ2=3.872，p=0.049）；세균감염조중57례환자재항감염치료전PCT적양성솔시100%(57/57)，경항균약물치료후PCT양성솔현저하강，위14.03%（8/57）。결론혈청PCT검측대HBV-ACLF병발세균감염적조기진단유중요개치，병능지도항균약물진행항균치료。
Objective: To investigate the role of PCT in early diagnosing and antibiotic treatment in HBV-ACLF concurrent bacterial infection. Methods: we chose 98 patients with chronic HBV-ACLF as the research object,and Al patients were come from our Hospital Infection department from January 2011 to January 2013. the patients were divided into bacterial infection and non-bacterial infection group through bacterial culture results,We detected the PCT and CRP‘s level in two groups of patients,and observed the PCT-positive bacterial infections after antimicrobial treatment of patients.Results:The Probability of PCT positive in bacterial infection group was significantly higher than the non-bacterial infection group (91.94% vs19.44%,χ2= 52.824, p = 0.000), And the probability of CRP positive in bacterial infection group and non-bacterial infection group had no significant difference (83.87%vs 66.67%,χ2 = 3.872, p = 0.049); the 57 patients' PCT positive rate in bacterial infection group was 100% (57/57) before anti-infection treatment,and it was decreased significantly after antimicrobial treatment, 14.03% (8/57).Conclusion: The Serum PCT detection play an important role in the early diagnosis of the HBV-ACLF concurrent bacterial infection. it can guide antimicrobial drugs in antimicrobial treatment.
