中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2013年
19期
15-15,16
,共2页
非瓣膜病性心房纤颤%CRP%BNP%ET-1
非瓣膜病性心房纖顫%CRP%BNP%ET-1
비판막병성심방섬전%CRP%BNP%ET-1
Nonvalvular atrial fibrillation%CRP%BNP%ET-1
目的：探讨非瓣膜病性心房纤颤患者血清 CRP、BNP 及内皮素-1水平及其临床意义。方法：选择2010年3月-2013年3月笔者所在医院诊治的80例非瓣膜病性心房纤颤(AF)患者，其中40例阵发性 AF 患者和40例慢性 AF 患者，作为 AF 组研究对象；另外选取同期40例窦性心律者，作为对照组研究对象，检测和比较各组血清 CRP、BNP 及内皮素-1水平。结果：与对照组相比，AF 组血清 CRP、BNP 及内皮素-1水平均明显升高，差异有统计学意义(P<0.05)；与阵发性 AF 组相比，慢性 AF 组血清 CRP、BNP 及内皮素-1水平也显著升高，差异有统计学意义(P<0.05)。结论：AF 患者血清 CRP、BNP 及内皮素-1水平明显升高，并且随着病情加重，其升高程度越明显。
目的：探討非瓣膜病性心房纖顫患者血清 CRP、BNP 及內皮素-1水平及其臨床意義。方法：選擇2010年3月-2013年3月筆者所在醫院診治的80例非瓣膜病性心房纖顫(AF)患者，其中40例陣髮性 AF 患者和40例慢性 AF 患者，作為 AF 組研究對象；另外選取同期40例竇性心律者，作為對照組研究對象，檢測和比較各組血清 CRP、BNP 及內皮素-1水平。結果：與對照組相比，AF 組血清 CRP、BNP 及內皮素-1水平均明顯升高，差異有統計學意義(P<0.05)；與陣髮性 AF 組相比，慢性 AF 組血清 CRP、BNP 及內皮素-1水平也顯著升高，差異有統計學意義(P<0.05)。結論：AF 患者血清 CRP、BNP 及內皮素-1水平明顯升高，併且隨著病情加重，其升高程度越明顯。
목적：탐토비판막병성심방섬전환자혈청 CRP、BNP 급내피소-1수평급기림상의의。방법：선택2010년3월-2013년3월필자소재의원진치적80례비판막병성심방섬전(AF)환자，기중40례진발성 AF 환자화40례만성 AF 환자，작위 AF 조연구대상；령외선취동기40례두성심률자，작위대조조연구대상，검측화비교각조혈청 CRP、BNP 급내피소-1수평。결과：여대조조상비，AF 조혈청 CRP、BNP 급내피소-1수평균명현승고，차이유통계학의의(P<0.05)；여진발성 AF 조상비，만성 AF 조혈청 CRP、BNP 급내피소-1수평야현저승고，차이유통계학의의(P<0.05)。결론：AF 환자혈청 CRP、BNP 급내피소-1수평명현승고，병차수착병정가중，기승고정도월명현。
Objective:To study the clinical significance of serum C-reactive protein,brain natriuretic peptide and endothelin-1 for patients with nonvalvular atrial fibrillation(AF).Methods:The 80 patients with AF including 40 patients of paroxysmal AF and 40 patients of chronic AF in our hospital during the period from March 2010 to March 2013 were regard as the AF group.The other 40 patients with sinus rhythm in the same period were regarded as the control group.The serum C-reactive protein(CRP),brain natriuretic peptide(BNP) and endothelin-1(ET-1) in the all groups were measured and compared.Results:Compared with the control group,the serum CRP,BNP and ET-1 levels were significantly increased in the AF group(P<0.05);Compared with the paroxysmal AF group,the CRP,BNP and ET-1 levels were significantly increased in the chronic AF group(P<0.05).Conclusion:For the AF patients,the serum CRP,BNP and ET-1 levels are significantly increased and the increase degree of serum CRP,BNP and ET-1 levels is more obvious with the increase of lesion degree.
