中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2013年
19期
10-11,12
,共3页
丁苯酞软胶囊%银杏达莫%急性脑梗死
丁苯酞軟膠囊%銀杏達莫%急性腦梗死
정분태연효낭%은행체막%급성뇌경사
Butylphtalide soft capsules%Ginkgo leaf extract and dipyridamole injection%Acute cerebral infarction
目的:观察丁苯酞联合银杏达莫治疗急性脑梗死的疗效和安全性。方法:将72例急性脑梗死患者随机分为 A、B、C 组,在常规治疗基础上,A 组给予丁苯酞软胶囊口服和银杏达莫静脉滴注,B 组给予银杏达莫静脉滴注,疗程、用法相同,C 组给予常规治疗,三组均治疗14 d。在治疗开始前、治疗结束后分别行临床神经功能缺损评分(NIHSS)和日常生活活动能力量表(BI)评分,观察和比较各组治疗效果,并对出现的不良反应进行评估。结果:A、B、C 组经治疗后 NIHSS 和 BI 评分均明显低于治疗前(P<0.05),A 组治疗后 NIHSS 和 BI 评分显著低于 B、C 组(P<0.05)。A 组治疗有效率(87.50%)明显优于 B 组(75.00%),差异有统计学意义(P<0.05)。结论:联合应用丁苯酞和银杏达莫对脑梗死急性发作期患者具有一定程度的协同治疗效果,而且临床应用较安全。
目的:觀察丁苯酞聯閤銀杏達莫治療急性腦梗死的療效和安全性。方法:將72例急性腦梗死患者隨機分為 A、B、C 組,在常規治療基礎上,A 組給予丁苯酞軟膠囊口服和銀杏達莫靜脈滴註,B 組給予銀杏達莫靜脈滴註,療程、用法相同,C 組給予常規治療,三組均治療14 d。在治療開始前、治療結束後分彆行臨床神經功能缺損評分(NIHSS)和日常生活活動能力量錶(BI)評分,觀察和比較各組治療效果,併對齣現的不良反應進行評估。結果:A、B、C 組經治療後 NIHSS 和 BI 評分均明顯低于治療前(P<0.05),A 組治療後 NIHSS 和 BI 評分顯著低于 B、C 組(P<0.05)。A 組治療有效率(87.50%)明顯優于 B 組(75.00%),差異有統計學意義(P<0.05)。結論:聯閤應用丁苯酞和銀杏達莫對腦梗死急性髮作期患者具有一定程度的協同治療效果,而且臨床應用較安全。
목적:관찰정분태연합은행체막치료급성뇌경사적료효화안전성。방법:장72례급성뇌경사환자수궤분위 A、B、C 조,재상규치료기출상,A 조급여정분태연효낭구복화은행체막정맥적주,B 조급여은행체막정맥적주,료정、용법상동,C 조급여상규치료,삼조균치료14 d。재치료개시전、치료결속후분별행림상신경공능결손평분(NIHSS)화일상생활활동능역량표(BI)평분,관찰화비교각조치료효과,병대출현적불량반응진행평고。결과:A、B、C 조경치료후 NIHSS 화 BI 평분균명현저우치료전(P<0.05),A 조치료후 NIHSS 화 BI 평분현저저우 B、C 조(P<0.05)。A 조치료유효솔(87.50%)명현우우 B 조(75.00%),차이유통계학의의(P<0.05)。결론:연합응용정분태화은행체막대뇌경사급성발작기환자구유일정정도적협동치료효과,이차림상응용교안전。
Objective:To evaluate the clinical efficacy and safty of combined use of butylphtalide soft capsules and ginkgo leaf extract and dipyridamole injection in the treatment of acute cerebral infarction.Methods:72 cases of acute cerebral infarction were randomly divided into A,B,C groups,on the basis of routine treatment,A group was given butylphthalide soft capsules orally and ginkgo leaf extract and ginkgo leaf extract and dipyridamole injection infusion, B group was given ginkgo leaf extract and dipyridamole injection infusion,treatment,using of the same,C group was given runtine treatment,three groups were treated for 14 days.In the end before starting treatment,after treatment,clinical neural function defect score(NIHSS) and activities of daily living scale (BI) score,observed and compared the treatment effect,and to evaluate the adverse effects.Results:A,B,C groups after treatment,NIHSS and BI scores were significantly lower than that before treatment(P<0.05),after treatment in A group,NIHSS and BI were significantly lower in B and C groupss (P<0.05).In A group, the treatment efficiency(87.50%) was significantly higher than that of B group(75.00%),there was significant difference (P<0.05).Conclusion:The combined application of butylphthalide and ginkgo leaf extract and dipyridamole injection on acute cerebral infarction onset synergistic therapeutic effect with a certain degree of patients,but the clinical application is safe.