医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
19期
126-127
,共2页
冠心病%黄芪%内皮素-1%超氧化物歧化酶%一氧化氮
冠心病%黃芪%內皮素-1%超氧化物歧化酶%一氧化氮
관심병%황기%내피소-1%초양화물기화매%일양화담
Coronary heart diseases (CHD)%Astraglus%Endothelin-1 (ET-1)%Superoxide dismutase (SOD)%Ntric oxide (NO)
目的探讨了黄芪对CHD患者血浆ET-1和血清SOD、NO水平的影响。方法应用放射免疫分析法和化学法对32例CHD患者进行了血浆ET-1和血清SOD、NO水平检测,并与35名正常健康人作比较。结论CHD患者在治疗前血浆ET-1水平非常显著地高于正常人组(P<0.01),而血清SOD、NO水平又非常显著地低于正常人组(P<0.01),经治疗三个月后则与正常人比较无显著性差异(P>0.05),结论应用黄芪治疗CHD患者有降低ET-1水平和升高SOD、NO水平作用,具有重要的临床价值。
目的探討瞭黃芪對CHD患者血漿ET-1和血清SOD、NO水平的影響。方法應用放射免疫分析法和化學法對32例CHD患者進行瞭血漿ET-1和血清SOD、NO水平檢測,併與35名正常健康人作比較。結論CHD患者在治療前血漿ET-1水平非常顯著地高于正常人組(P<0.01),而血清SOD、NO水平又非常顯著地低于正常人組(P<0.01),經治療三箇月後則與正常人比較無顯著性差異(P>0.05),結論應用黃芪治療CHD患者有降低ET-1水平和升高SOD、NO水平作用,具有重要的臨床價值。
목적탐토료황기대CHD환자혈장ET-1화혈청SOD、NO수평적영향。방법응용방사면역분석법화화학법대32례CHD환자진행료혈장ET-1화혈청SOD、NO수평검측,병여35명정상건강인작비교。결론CHD환자재치료전혈장ET-1수평비상현저지고우정상인조(P<0.01),이혈청SOD、NO수평우비상현저지저우정상인조(P<0.01),경치료삼개월후칙여정상인비교무현저성차이(P>0.05),결론응용황기치료CHD환자유강저ET-1수평화승고SOD、NO수평작용,구유중요적림상개치。
objective :To explore the effect of Astraglus of plasma ET-1 and Serum SOD 、NO levels in patients with Coronary heart diseases .Methods:plasma ET-1 and serum SOD (With RIA) serum NO(With chemistry) levels were measured in 32 patients with CHD .and 35 contrals .Results :Before treatment plasme ET-1 levels were significantly higher than those in Controls (p<0.01) ,but Serum SOD 、NO levels were significantly lower (p<0.01) , after treatment for 3 months the levels were slight difference from those in Controls (p>0.05) , Conclusions: application for Astraglus treatment were decrease of plasma ET-1 and serum SOD 、NO levels,be of important clinical value .