中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
20期
129-131,132
,共4页
马宏伟%邵成雷%魏永义%孙绪丁
馬宏偉%邵成雷%魏永義%孫緒丁
마굉위%소성뢰%위영의%손서정
前列宁胶囊%红花%诃子%菥蓂子%藏茜草%没食子酸%羟基红花黄色素 A
前列寧膠囊%紅花%訶子%菥蓂子%藏茜草%沒食子痠%羥基紅花黃色素 A
전렬저효낭%홍화%가자%석명자%장천초%몰식자산%간기홍화황색소 A
Qianliening Capsule%Flos Carthami%Terminalia Chebula%Semen Thlaspi%Radix et Rhizoma Rubiae%Gallic acid%Hydroxy Safflor yellow A
目的：研究并提高藏药前列宁胶囊的质量标准。方法：采用薄层色谱法鉴别红花、诃子、菥蓂子、藏茜草；采用高效液相色谱法同时测定没食子酸和羟基红花黄色素 A。结果：薄层色谱显色清晰，阴性对照无干扰。没食子酸在33.76~337.6μg/ml 浓度范围内线性关系良好，r=0.9996，平均加样回收率为98.35%，RSD 为1.36%。羟基红花黄色素 A 在2.68~26.80μg/ml 浓度范围内线性关系良好，r=0.9998，平均加样回收率为99.03%，RSD 为0.72%。结论：该方法简便、可行、可靠，可用于控制前列宁胶囊的质量。
目的：研究併提高藏藥前列寧膠囊的質量標準。方法：採用薄層色譜法鑒彆紅花、訶子、菥蓂子、藏茜草；採用高效液相色譜法同時測定沒食子痠和羥基紅花黃色素 A。結果：薄層色譜顯色清晰，陰性對照無榦擾。沒食子痠在33.76~337.6μg/ml 濃度範圍內線性關繫良好，r=0.9996，平均加樣迴收率為98.35%，RSD 為1.36%。羥基紅花黃色素 A 在2.68~26.80μg/ml 濃度範圍內線性關繫良好，r=0.9998，平均加樣迴收率為99.03%，RSD 為0.72%。結論：該方法簡便、可行、可靠，可用于控製前列寧膠囊的質量。
목적：연구병제고장약전렬저효낭적질량표준。방법：채용박층색보법감별홍화、가자、석명자、장천초；채용고효액상색보법동시측정몰식자산화간기홍화황색소 A。결과：박층색보현색청석，음성대조무간우。몰식자산재33.76~337.6μg/ml 농도범위내선성관계량호，r=0.9996，평균가양회수솔위98.35%，RSD 위1.36%。간기홍화황색소 A 재2.68~26.80μg/ml 농도범위내선성관계량호，r=0.9998，평균가양회수솔위99.03%，RSD 위0.72%。결론：해방법간편、가행、가고，가용우공제전렬저효낭적질량。
Objective:To study and upgrade the quality standard of Tibetan Medicine Qianliening Capsule.Method:TLC method was used to identify Flos Carthami,Terminalia Chebula,Semen Thlaspi and Radix et Rhizoma Rubiae;Hplc was used for the determination of Gallic acid and Hydroxy Safflor yellow A.Result:Flos Carthami,Terminalia Chebula,Semen Thlaspi and Radix et Rhizoma Rubiae could be identified by TLC without the interference of negative control.Gallic acid and Hydroxy Safflor yellow A could be determined at the same time.Gallic acid was linear in the concentration range of 33.76-337.6μg/mL,r=0.9996.The average recovery rate was 98.35%,RSD=1.36%;Hydroxy Safflor yellow A had a good linear in the concentration range of 2.68-26.80 μg/ml,r=0.9998.The average recovery rate was 99.03%,RSD=0.72%.Conclusion:The method is simple, feasible,reliable,and can be effectively used for the quality control of Qianliening Capsule.
