当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
20期
156-157
,共2页
异位妊娠%中药%甲氨喋呤
異位妊娠%中藥%甲氨喋呤
이위임신%중약%갑안첩령
Ectopic pregnancy%Chinese medicine%Methotrexate
目的观察两种中药方剂联合甲氨喋呤（MTX）治疗异位妊娠的作用。方法未破裂异位妊娠，根据不同中药方剂分为A、B组：A组30例，采用治疗宫外孕中药方剂Ⅰ号联合MTX 50 mg 单剂量注射；B组30例，采用治疗宫外孕中药方剂Ⅱ号联合MTX 50 mg 单剂量注射。结果 A、B组成功率分别为90.％、83.33％。2组比较无差异。但A组疗程成功率明显高于B组，且血β-HCG下降时间（d）A组：（19±5）；B组(26±5)。血β-HCG恢复正常时间明显缩短，（P<0.05）。B组妊娠包块吸收时间明显缩短，差异有统计学意义（P<0.05）。结论宫外孕中药方剂Ⅰ号联合MTX单次用药较宫外孕中药方剂Ⅱ号联合MTX单次用药β-HCG下降速度快，但后者妊娠包块吸收快。较MTX单次用药，剂量较小，相对不良反应轻。
目的觀察兩種中藥方劑聯閤甲氨喋呤（MTX）治療異位妊娠的作用。方法未破裂異位妊娠，根據不同中藥方劑分為A、B組：A組30例，採用治療宮外孕中藥方劑Ⅰ號聯閤MTX 50 mg 單劑量註射；B組30例，採用治療宮外孕中藥方劑Ⅱ號聯閤MTX 50 mg 單劑量註射。結果 A、B組成功率分彆為90.％、83.33％。2組比較無差異。但A組療程成功率明顯高于B組，且血β-HCG下降時間（d）A組：（19±5）；B組(26±5)。血β-HCG恢複正常時間明顯縮短，（P<0.05）。B組妊娠包塊吸收時間明顯縮短，差異有統計學意義（P<0.05）。結論宮外孕中藥方劑Ⅰ號聯閤MTX單次用藥較宮外孕中藥方劑Ⅱ號聯閤MTX單次用藥β-HCG下降速度快，但後者妊娠包塊吸收快。較MTX單次用藥，劑量較小，相對不良反應輕。
목적관찰량충중약방제연합갑안첩령（MTX）치료이위임신적작용。방법미파렬이위임신，근거불동중약방제분위A、B조：A조30례，채용치료궁외잉중약방제Ⅰ호연합MTX 50 mg 단제량주사；B조30례，채용치료궁외잉중약방제Ⅱ호연합MTX 50 mg 단제량주사。결과 A、B조성공솔분별위90.％、83.33％。2조비교무차이。단A조료정성공솔명현고우B조，차혈β-HCG하강시간（d）A조：（19±5）；B조(26±5)。혈β-HCG회복정상시간명현축단，（P<0.05）。B조임신포괴흡수시간명현축단，차이유통계학의의（P<0.05）。결론궁외잉중약방제Ⅰ호연합MTX단차용약교궁외잉중약방제Ⅱ호연합MTX단차용약β-HCG하강속도쾌，단후자임신포괴흡수쾌。교MTX단차용약，제량교소，상대불량반응경。
Objective To observe the effect of two kinds of Chinese herbal medicine combined with methotrexate ( MTX ) in the treatment of ectopic pregnancy. Methods According to the different prescription of traditional Chinese medicine,60 cases with unruptured ectopic pregnancy, were divided into two groups:group A 30 cases, were treated with traditional Chinese medical herbs ( referred to as ectopic pregnanc y) and MTX 50 mg single dose intramuscular injection;30 cases in group B, treated ectopic pregnancy prescription ( referred to as EPII ) combined with MTX 50 mg single dose intramuscular injection. Results Success rates of group A, B were respectively 90.00%, 83.33%. There had no significant difference between two groups ( P>0.05 ). But one course of treatment success rate of group A was higher than that in group B, And the bloodβ-HCG fall time (d) of A group:(19 ± 5);(26 ± 5) in group B. The bloodβ-HCG recovery time shortened obviously, (P<0.05). there were signiifcant differences. Gestation mass absorption time obviously shortened in group B, there were significant difference(P<0.05). Conclusion β -HCG decrease faster using ectopic pregnancyⅠcombined with MTX single drug than EPII combined with MTX single dose of , but the latter pregnancy bag piece fast absorption. MTX is only a single dose, low dose, relatively mild side effects.
