当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
20期
1-2
,共2页
β-七叶皂苷钠%甘露醇%蛛网膜下隙出血%颅内压%并发症
β-七葉皂苷鈉%甘露醇%蛛網膜下隙齣血%顱內壓%併髮癥
β-칠협조감납%감로순%주망막하극출혈%로내압%병발증
β-aescine sodium%Mannitol%Subarachnoid hemorrhage%Intracranial pressure%Complication
目的分析β-七叶皂苷钠联合甘露醇治疗颅脑损伤后蛛网膜下隙出血的效果。方法将东莞市人民医院2009年1月-2012年6月神经外科收治的颅脑损伤后蛛网膜下隙出血患者100例,随机分为观察组和对照组,各50例。对照组给予抗生素及20%的甘露醇250 mL静脉滴注,4次/d,持续7 d后减量,14 d停药,观察组在此基础上给予给予20 mg β-七叶皂苷钠加入5%葡萄糖250 mL,每日1次,静脉滴注,疗程14 d。比较治疗前后两组患者的颅内压情况及并发症的发生情况。结果与对照组比较,观察组颅内压的降低效果更明显(P<0.05,有统计学意义),治疗后再出血、血管痉挛和脑水肿的发生率明显降低(P<0.05,有统计学意义)。结论用β-七叶皂苷钠联合甘露醇治疗蛛网膜下隙出血的颅脑损伤患者能起到降低颅内压及减少并发症的作用。
目的分析β-七葉皂苷鈉聯閤甘露醇治療顱腦損傷後蛛網膜下隙齣血的效果。方法將東莞市人民醫院2009年1月-2012年6月神經外科收治的顱腦損傷後蛛網膜下隙齣血患者100例,隨機分為觀察組和對照組,各50例。對照組給予抗生素及20%的甘露醇250 mL靜脈滴註,4次/d,持續7 d後減量,14 d停藥,觀察組在此基礎上給予給予20 mg β-七葉皂苷鈉加入5%葡萄糖250 mL,每日1次,靜脈滴註,療程14 d。比較治療前後兩組患者的顱內壓情況及併髮癥的髮生情況。結果與對照組比較,觀察組顱內壓的降低效果更明顯(P<0.05,有統計學意義),治療後再齣血、血管痙攣和腦水腫的髮生率明顯降低(P<0.05,有統計學意義)。結論用β-七葉皂苷鈉聯閤甘露醇治療蛛網膜下隙齣血的顱腦損傷患者能起到降低顱內壓及減少併髮癥的作用。
목적분석β-칠협조감납연합감로순치료로뇌손상후주망막하극출혈적효과。방법장동완시인민의원2009년1월-2012년6월신경외과수치적로뇌손상후주망막하극출혈환자100례,수궤분위관찰조화대조조,각50례。대조조급여항생소급20%적감로순250 mL정맥적주,4차/d,지속7 d후감량,14 d정약,관찰조재차기출상급여급여20 mg β-칠협조감납가입5%포도당250 mL,매일1차,정맥적주,료정14 d。비교치료전후량조환자적로내압정황급병발증적발생정황。결과여대조조비교,관찰조로내압적강저효과경명현(P<0.05,유통계학의의),치료후재출혈、혈관경련화뇌수종적발생솔명현강저(P<0.05,유통계학의의)。결론용β-칠협조감납연합감로순치료주망막하극출혈적로뇌손상환자능기도강저로내압급감소병발증적작용。
Objective To study the clinical efifcacy ofβ-aescine sodium combined with mannitol in the treatment of subarachnoid hemorrhage after brain injury.Methods One hundred patients with severe brain injury admitted to the hospital from January 2009 to June 2012 were randomly divided into observation group (50 cases) and control group (50 cases) . The control group was routinely given 20%mannitol and anti-infection treatment. While the observation group was givenβ-aescine sodium ,and the intracranial pressure and complication was observed. Results The intracranial pressure and complication was significantly decreased in the observation group compared with control group(P<0.05).Conclusionβ-aescine sodium combined with mannitol can signiifcant reduce the intracranial pressure and complication.