西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2014年
5期
99-101
,共3页
ARDS%麻黄附子细辛汤%治疗,临床研究性
ARDS%痳黃附子細辛湯%治療,臨床研究性
ARDS%마황부자세신탕%치료,림상연구성
ARDS%MaHuangFuZiXiXindecoction%treatment,clinical study
目的：观察麻黄附子细辛汤治疗急性呼吸窘迫综合征(ARDS)的疗效。方法：将ICU收治的ARDS患者126例按随机数字表法分为治疗组和对照组各63例，2组患者均予控制原发病的治疗，治疗组在此基础上予麻黄附子细辛汤每日1～2剂口服或鼻饲。治疗3周对2组患者基本情况评分及应用抗生素时间，抗生素使用率，抗生素使用强度（DDDS）以及血管活性药物、肾上腺皮质激素应用时间，机械通气时间，ICU住院时间，死亡率等进行比较。结果：治疗后Marshall评分治疗组为（5.23±2.25）分，与对照组（6.10±1.42）分比较P＜0.05；APACHEⅡ评分治疗组为（10.36±4.78）分，与对照组(14.31±2.13)分比较P＜0.05；PaO2/FiO2治疗组为（342.00±56.34）mmHg，与对照组（296.00±42.63）mmHg比较（P＜0.05）；2组应用抗生素时间、抗生素使用率、DDDS、血管活性药物应用时间，机械通气时间、死亡率、ICU住院时间等比较差异具有统计学意义（P＜0.05）。结论：在治疗原发病基础上采用麻黄附子细辛汤治疗ARDS安全有效。
目的：觀察痳黃附子細辛湯治療急性呼吸窘迫綜閤徵(ARDS)的療效。方法：將ICU收治的ARDS患者126例按隨機數字錶法分為治療組和對照組各63例，2組患者均予控製原髮病的治療，治療組在此基礎上予痳黃附子細辛湯每日1～2劑口服或鼻飼。治療3週對2組患者基本情況評分及應用抗生素時間，抗生素使用率，抗生素使用彊度（DDDS）以及血管活性藥物、腎上腺皮質激素應用時間，機械通氣時間，ICU住院時間，死亡率等進行比較。結果：治療後Marshall評分治療組為（5.23±2.25）分，與對照組（6.10±1.42）分比較P＜0.05；APACHEⅡ評分治療組為（10.36±4.78）分，與對照組(14.31±2.13)分比較P＜0.05；PaO2/FiO2治療組為（342.00±56.34）mmHg，與對照組（296.00±42.63）mmHg比較（P＜0.05）；2組應用抗生素時間、抗生素使用率、DDDS、血管活性藥物應用時間，機械通氣時間、死亡率、ICU住院時間等比較差異具有統計學意義（P＜0.05）。結論：在治療原髮病基礎上採用痳黃附子細辛湯治療ARDS安全有效。
목적：관찰마황부자세신탕치료급성호흡군박종합정(ARDS)적료효。방법：장ICU수치적ARDS환자126례안수궤수자표법분위치료조화대조조각63례，2조환자균여공제원발병적치료，치료조재차기출상여마황부자세신탕매일1～2제구복혹비사。치료3주대2조환자기본정황평분급응용항생소시간，항생소사용솔，항생소사용강도（DDDS）이급혈관활성약물、신상선피질격소응용시간，궤계통기시간，ICU주원시간，사망솔등진행비교。결과：치료후Marshall평분치료조위（5.23±2.25）분，여대조조（6.10±1.42）분비교P＜0.05；APACHEⅡ평분치료조위（10.36±4.78）분，여대조조(14.31±2.13)분비교P＜0.05；PaO2/FiO2치료조위（342.00±56.34）mmHg，여대조조（296.00±42.63）mmHg비교（P＜0.05）；2조응용항생소시간、항생소사용솔、DDDS、혈관활성약물응용시간，궤계통기시간、사망솔、ICU주원시간등비교차이구유통계학의의（P＜0.05）。결론：재치료원발병기출상채용마황부자세신탕치료ARDS안전유효。
Objective: To investigate therapeutic effects ofMaHuangFuZiXiXindecoction in treating acute respiratory distress syndrome (ARDS). Methods: All 126 patients admitted to ICU were allocated to the treatment group and the control group by random number table method, on the foundation of the treatment for primary disease, the treatment group receivedMaHuangFuZiXiXindecoction by mouth or nasal feeding. The scores of basic condi-tions of the patients in both groups, the time and the rate of using antibiotics, DDDS, the time of vasoactive agent, the time of adrenal cortex hormone, mechanical ventilation time, ICU hospitalization time, death rate and others were compared after treating for three weeks. Results: After treating, Marshall scores of the treatment group were (5.23±2.25), which were compared to (6.10±1.42) of the control groupP<0.05; APACHEⅡscores of the treatment group were (10.36±4.78), they were compared with (14.31±2.13) of the control groupP<0.05; PaO2/FiO2 of the treatment group were (342.00±56.34) mmHg, higher than(296.00±42.63)mmHg of the control groupP<0.05; the difference showed statistical meaning in the time and the rate of using antibiotics, DDDS, the time of vasoactive a-gent, mechanical ventilation time, death rate, ICU hospitalization time and others (P<0.05). Conclusion:MaHuang FuZiXiXindecoction is safe and effective in treating ARDS.
