中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
31期
5705-5710
,共6页
器官移植%器官移植学术探讨%椎间植骨%内固定%腰椎管狭窄症%后路减压%植骨融合%下腰痛%间歇性跛行%脑脊液漏%硬膜外血肿
器官移植%器官移植學術探討%椎間植骨%內固定%腰椎管狹窄癥%後路減壓%植骨融閤%下腰痛%間歇性跛行%腦脊液漏%硬膜外血腫
기관이식%기관이식학술탐토%추간식골%내고정%요추관협착증%후로감압%식골융합%하요통%간헐성파행%뇌척액루%경막외혈종
organ transplantation%organ transplantation academic discussion%intervertebral bone graft%internal fixation%lumbar spinal stenosis%posterior decompression%fusion%lower back pain%intermittent claudication%cerebrospinal fluid leak%epidural hematoma
背景：腰椎管狭窄症严重影响患者的下肢的活动及功能，甚至引起瘫痪。目的：评价椎间植骨内固定治疗腰椎管狭窄症的临床效果。方法：对应用后路减压椎间植骨内固定治疗腰椎管狭窄症的患者进行随访观察，通过评估患者临床症状和体征改善情况、神经功能恢复情况、椎间植骨融合情况以及并发症发生情况评价椎间植骨内固定治疗腰椎管狭窄症的效果，并比较应用后路减压椎间植骨内固定与单纯减压治疗腰椎管狭窄症的效果，以进一步明确椎间植骨内固定的治疗效果。结果与结论：对应用后路减压椎间植骨内固定治疗腰椎管狭窄症的患者进行随访观察，下腰痛、肢体局部感觉障碍以及间歇性跛行等症状明显改善，神经功能恢复评分可高达90%以上，影像学检查可见椎间植骨融合良好，神经、血管及硬膜损伤等并发症发生较少。比较研究显示，后路减压椎间植骨内固定治疗的优良率高达95.2%，而单纯减压治疗的优良率仅为23.8%，后路减压椎间植骨内固定的治疗效果明显优于单纯减压治疗。
揹景：腰椎管狹窄癥嚴重影響患者的下肢的活動及功能，甚至引起癱瘓。目的：評價椎間植骨內固定治療腰椎管狹窄癥的臨床效果。方法：對應用後路減壓椎間植骨內固定治療腰椎管狹窄癥的患者進行隨訪觀察，通過評估患者臨床癥狀和體徵改善情況、神經功能恢複情況、椎間植骨融閤情況以及併髮癥髮生情況評價椎間植骨內固定治療腰椎管狹窄癥的效果，併比較應用後路減壓椎間植骨內固定與單純減壓治療腰椎管狹窄癥的效果，以進一步明確椎間植骨內固定的治療效果。結果與結論：對應用後路減壓椎間植骨內固定治療腰椎管狹窄癥的患者進行隨訪觀察，下腰痛、肢體跼部感覺障礙以及間歇性跛行等癥狀明顯改善，神經功能恢複評分可高達90%以上，影像學檢查可見椎間植骨融閤良好，神經、血管及硬膜損傷等併髮癥髮生較少。比較研究顯示，後路減壓椎間植骨內固定治療的優良率高達95.2%，而單純減壓治療的優良率僅為23.8%，後路減壓椎間植骨內固定的治療效果明顯優于單純減壓治療。
배경：요추관협착증엄중영향환자적하지적활동급공능，심지인기탄탄。목적：평개추간식골내고정치료요추관협착증적림상효과。방법：대응용후로감압추간식골내고정치료요추관협착증적환자진행수방관찰，통과평고환자림상증상화체정개선정황、신경공능회복정황、추간식골융합정황이급병발증발생정황평개추간식골내고정치료요추관협착증적효과，병비교응용후로감압추간식골내고정여단순감압치료요추관협착증적효과，이진일보명학추간식골내고정적치료효과。결과여결론：대응용후로감압추간식골내고정치료요추관협착증적환자진행수방관찰，하요통、지체국부감각장애이급간헐성파행등증상명현개선，신경공능회복평분가고체90%이상，영상학검사가견추간식골융합량호，신경、혈관급경막손상등병발증발생교소。비교연구현시，후로감압추간식골내고정치료적우량솔고체95.2%，이단순감압치료적우량솔부위23.8%，후로감압추간식골내고정적치료효과명현우우단순감압치료。
BACKGROUND:Lumbar spinal stenosis can severely affect the activities and functions of the lower limbs, and even cause paralysis. OBJECTIVE:To evaluate the clinical effect of intervertebral bone graft with internal fixation for the treatment of lumbar spinal stenosis. METHODS:The lumbar spinal stenosis patients treated with posterior decompression and intervertebral bone graft with internal fixation were fol owed-up. The effect of intervertebral bone graft with internal fixation for the treatment of lumbar spinal stenosis was evaluated through assessing the clinical symptoms and improvement of signs, recovery of neurological function, as wel as intervertebral bone graft and fusion and the occurrence of complications. The effects of posterior decompression and intervertebral bone graft with internal fixation and simple decompression for the treatment of lumbar spinal stenosis were compared, in order to further determine the treatment of intervertebral bone graft with internal fixation. RESUTLS AND CONCLUSION:The fol ow-up results of the lumbar spinal stenosis patients treated with posterior decompression and intervertebral bone graft with internal fixation showed that the symptoms of low back pain, partial limb sensory disturbances and intermittent claudication were improved significantly;the neurological recovery score could be up to 90%or above. Radiographic examination showed good intervertebral bone graft and fusion with less complication of nerves, blood vessels and dural injury. Comparative study showed that the excel ent and good rate of posterior decompression and intervertebral bone graft with internal fixation can reach to 95.2%, while the excel ent and good rate of simple decompression was 23.8%, indicating that the effect of posterior decompression and intervertebral bone graft with internal fixation was significantly better than that of simple decompression.
