CAJ | 학술논문

　　目的初步观察我军健康现役飞行员中心动脉反射增强指数(augmentation index,AIx)的变化及其影响因素，为招飞及现役飞行员心血管疾病的预防、治疗提供参考。方法采用无创主动脉搏波分析仪(Sphygmocor)对在空军总医院住院、体检、改装的58例现役飞行员中心动脉收缩压（cSBP）及AIx进行定量检测，并随机选择住院体检的63例健康男性人群作为对照组，两组间进行年龄、血压配对比较无差异，并经病史询问无心血管疾病史，体格检查无阳性体征。心电图、X线胸片、肝肾功能、生化全套等检查无异常者。结果两组间临床资料及生化检测指标的比较无统计学差异（P>0.05），健康飞行员组AIx值低于对照组（P<0.05），相关性分析结果表明AIx与年龄呈正相关（飞行员组：r=0.367，P<0.05）。多元逐步回归分析示年龄、cSBP、收缩压、舒张压是健康飞行员AIx 的主要影响因素。结论健康飞行员AIx值低于正常健康人，但受年龄、cSBP、收缩压、舒张压影响。AIx值可为招飞及飞行员心血管疾病的预防、治疗提供理论参考。
　　목적초보관찰아군건강현역비행원중심동맥반사증강지수(augmentation index,AIx)적변화급기영향인소，위초비급현역비행원심혈관질병적예방、치료제공삼고。방법채용무창주동맥박파분석의(Sphygmocor)대재공군총의원주원、체검、개장적58례현역비행원중심동맥수축압（cSBP）급AIx진행정량검측，병수궤선택주원체검적63례건강남성인군작위대조조，량조간진행년령、혈압배대비교무차이，병경병사순문무심혈관질병사，체격검사무양성체정。심전도、X선흉편、간신공능、생화전투등검사무이상자。결과량조간림상자료급생화검측지표적비교무통계학차이（P>0.05），건강비행원조AIx치저우대조조（P<0.05），상관성분석결과표명AIx여년령정정상관（비행원조：r=0.367，P<0.05）。다원축보회귀분석시년령、cSBP、수축압、서장압시건강비행원AIx 적주요영향인소。결론건강비행원AIx치저우정상건강인，단수년령、cSBP、수축압、서장압영향。AIx치가위초비급비행원심혈관질병적예방、치료제공이론삼고。
Objective We intended to observe the changes of augmentation index (AIx) of central artery and its influence factors in healthy military pilots, to provide reference for pilot recruitment, and to present references for prevention and treatment of cardiovascular diseases in active pilots. Methods Using Sphygmocor, the central artery systolic blood pressure (cSBP) and AIx were quantitatively detected in 58 active pilots who were hospitalized or took physical examination for pilot transition. Forty-nine healthy male subjects who were hospitalized for physical examination were randomly selected as control group. There were no differences between two groups regarding age and blood pressure. They had no history of cardiovascular diseases, and had no positive signs during physical examination, and had no abnormal results regarding ECG, chest x-ray, hepatic function, kidney function and biochemistry panel. Results Between the two groups, there were no statistically significant differences regarding clinical data and biochemistry index (P>0.05). With regard to AIx value, it was lower in healthy pilot group than that in control group (P<0.05). Correlation analysis revealed that AIx was positively correlated with age (pilot group, r=0.367, P<0.05). The multiple stepwise regression analysis showed that age, cSBP, systolic blood pressure and diastolic blood pressure were main influencial factors of AIx in healthy pilots. Conclusions In healthy pilots, the AIx value was lower than that in healthy subjects, but it was influenced by age, cSBP, systolic blood pressure and diastolic blood pressure. The AIx value could provided theory references for pilot recruitment and prevention and treatment of cardiovascular diseases in pilots.