CAJ | 학술논문

　　目的探讨原发性腹膜后肿瘤（primary retroperitoneal tumor，PRT）患者手术切除预后的影响因素。方法回顾性分析2001年6月至2012年6月住院治疗的80例原发性腹膜后肿瘤患者的临床病理资料，采用Kaplan-Meier方法、Cox比例风险回归模型和Log-rank检验，分析影响PRT患者预后的相关因素。结果本组病例均获随访，中位随访时间为40.4个月，1年、3年、5年累计生存率分别为92.5%、73.1%、67.5%，中位生存时间为67个月。单因素分析显示，手术方式、肿瘤大小、肿瘤性质、有丝分裂数、周围器官侵犯等因素影响PRT患者术后累计生存率（P<0.05）。多因素分析显示，手术方式、肿瘤性质、有丝分裂数、周围器官侵犯等是影响PRT预后的独立影响因素（P<0.05）。结论手术切除是PRT患者有效的治疗手段，肿瘤性质、手术方式、周围器官侵犯、有丝分裂数是影响PRT预后的独立影响因素。
　　목적탐토원발성복막후종류（primary retroperitoneal tumor，PRT）환자수술절제예후적영향인소。방법회고성분석2001년6월지2012년6월주원치료적80례원발성복막후종류환자적림상병리자료，채용Kaplan-Meier방법、Cox비례풍험회귀모형화Log-rank검험，분석영향PRT환자예후적상관인소。결과본조병례균획수방，중위수방시간위40.4개월，1년、3년、5년루계생존솔분별위92.5%、73.1%、67.5%，중위생존시간위67개월。단인소분석현시，수술방식、종류대소、종류성질、유사분렬수、주위기관침범등인소영향PRT환자술후루계생존솔（P<0.05）。다인소분석현시，수술방식、종류성질、유사분렬수、주위기관침범등시영향PRT예후적독립영향인소（P<0.05）。결론수술절제시PRT환자유효적치료수단，종류성질、수술방식、주위기관침범、유사분렬수시영향PRT예후적독립영향인소。
Objective To explore the prognostic factors of patients with primary retroperitoneal tumor (PRT)treated by surgical re-section. Methods We retrospectively analyzed 80 patients with PRT treated in the First Affiliated Hospital of Guangxi Medical Uni-versity between June 2001 and June 2012.Survival and prognosis were analyzed using the Kaplan-Meier method,the Cox proportional hazard model and the log-rank test. Results All patients were followed up for a median of 40.4 months,and the 1-,3-,and 5-year cumulative survival rates were 92.5%,73.1% and 67.5%.Median survival time was 67 months. Univariate analysis identified the fol-lowing significant predictors of survival(P<0.05):surgical method,tumor size,tumor characteristics,mitotic counts of tumor cells,and invasion of adjacent organs.Multivariate analysis identified the following independent prognostic factors(P<0.05):surgical method, tumor characteristics,mitotic counts of the tumor cells and invasion of adjacent organs. Conclusion Surgical resection is the most ef-fective treatment for PRT.Tumor characteristics,surgical method,invasion of adjacent organs and mitotic counts of tumor cells are the most important prognostic factors for PRT.