湖南师范大学学报（医学版）
湖南師範大學學報（醫學版）
호남사범대학학보（의학판）
JOURNAL OF HUNAN NORMAL UNIVERSITY(MEDICAL SCIENCE)
2013年
2期
58-60
,共3页
罗启占%张晓波%陈雄%戴元清
囉啟佔%張曉波%陳雄%戴元清
라계점%장효파%진웅%대원청
坦索罗辛%非那雄胺%前列腺增生症%焦虑%睡眠%生活质量
坦索囉辛%非那雄胺%前列腺增生癥%焦慮%睡眠%生活質量
탄색라신%비나웅알%전렬선증생증%초필%수면%생활질량
tamsulosin%finasteride%BPH%anxiety%sleeping%QOLS
目的：探讨坦索罗辛0.2mg联合非那雄胺5mg对老年前列腺增生症患者的焦虑及睡眠的影响。方法：观察35例老年前列腺增生症患者。年龄56-84岁,平均70岁。入选的35例BPH患者，口服坦索罗辛0.2mg加非那雄胺5mg，疗程三个月，观察患者服药前和服药后的国际前列腺症状评分表IPSS、焦虑程度SAS、阿森斯失眠量表AIS及生活质量评分表QOLS。结果：服药前有19例（54.3%）伴焦虑，服药后10例（28.57%）伴焦虑；服药前16例（45.71%）伴失眠，服药后8例（22.86%)伴失眠。服药前、服药后患者焦虑、睡眠障碍发生率比较，差异,有统计学意义。服药前后IPSS从25.00±3.93到15.85±3.51、SAS从38.06±6.10到26.50±5.72，AIS从10.60±5.06到5.00±4.22，QOLS从3.95±0.76到3.10±0.641，治疗前后比较有统计学意义。结论：坦索罗辛联合非那雄胺治疗前列腺患者能够缓解下尿路症状，改善老年前列腺增生症患者的焦虑、睡眠及生活质量。
目的：探討坦索囉辛0.2mg聯閤非那雄胺5mg對老年前列腺增生癥患者的焦慮及睡眠的影響。方法：觀察35例老年前列腺增生癥患者。年齡56-84歲,平均70歲。入選的35例BPH患者，口服坦索囉辛0.2mg加非那雄胺5mg，療程三箇月，觀察患者服藥前和服藥後的國際前列腺癥狀評分錶IPSS、焦慮程度SAS、阿森斯失眠量錶AIS及生活質量評分錶QOLS。結果：服藥前有19例（54.3%）伴焦慮，服藥後10例（28.57%）伴焦慮；服藥前16例（45.71%）伴失眠，服藥後8例（22.86%)伴失眠。服藥前、服藥後患者焦慮、睡眠障礙髮生率比較，差異,有統計學意義。服藥前後IPSS從25.00±3.93到15.85±3.51、SAS從38.06±6.10到26.50±5.72，AIS從10.60±5.06到5.00±4.22，QOLS從3.95±0.76到3.10±0.641，治療前後比較有統計學意義。結論：坦索囉辛聯閤非那雄胺治療前列腺患者能夠緩解下尿路癥狀，改善老年前列腺增生癥患者的焦慮、睡眠及生活質量。
목적：탐토탄색라신0.2mg연합비나웅알5mg대노년전렬선증생증환자적초필급수면적영향。방법：관찰35례노년전렬선증생증환자。년령56-84세,평균70세。입선적35례BPH환자，구복탄색라신0.2mg가비나웅알5mg，료정삼개월，관찰환자복약전화복약후적국제전렬선증상평분표IPSS、초필정도SAS、아삼사실면량표AIS급생활질량평분표QOLS。결과：복약전유19례（54.3%）반초필，복약후10례（28.57%）반초필；복약전16례（45.71%）반실면，복약후8례（22.86%)반실면。복약전、복약후환자초필、수면장애발생솔비교，차이,유통계학의의。복약전후IPSS종25.00±3.93도15.85±3.51、SAS종38.06±6.10도26.50±5.72，AIS종10.60±5.06도5.00±4.22，QOLS종3.95±0.76도3.10±0.641，치료전후비교유통계학의의。결론：탄색라신연합비나웅알치료전렬선환자능구완해하뇨로증상，개선노년전렬선증생증환자적초필、수면급생활질량。
Objective To evaluate the effect of tamsulosin (0.2mg) and finasteride (0.5mg) on anxiety and sleeping for benign prostate hypertrophy patients . Metheods Observed 35 benign prostate hypertrophy patients Patients were treated with tamsulosin 0.2mg,qd and combined with finasteride 0.2mg,qd for 3 months . IPSS,SAS, AIS and QOLS were measured before and after the treatment. Results Before taking the medicine, 19 cases (54.3%) with anxiety, after the treatment,10cases (28.57%) with anxiety ; Before taking the medicine16cases (45.71%) with insomnia , after the treatment, 16 cases (45.71%) with insomnia. There was significant difference between before the treatment and after the treatment. P<0.05 .Before the treatment ,average IPSS 25.00±3.93, av-erage SAS 38.06±6.10, average AIS 10.60±5.06, and average QOLS 3.95±0.76;After 3 months treatment , average IPSS 15.85±3.51. average SAS 26.50±5.72, average AIS 5.00±4.22 and average QOLS 3.10±0.641. There was significant difference between before the treatment and after the treatment. P<0.05. Conclusion Treatment of benign prostatic hyperplasia (BPH) with tamsulosin hydrochloride Sustained-Release Capsules combined with fi-nasteride Tablets could relieve lower urinary tract symptoms, improve anxiety, sleeping and the quality of life
