CAJ | 학술논문

　　目的：评价非高危因素的腹腔镜下胆囊切除术（LC）患者预防应激性溃疡（SU）的必要性，为临床合理用药提供参考。方法：将90例非高危因素的腹腔镜下胆囊切除术患者按1：2的比例随机分为未用药组和用药组，并进行回顾性分析：术后SU的发生率；住院时间、住院费用、药品费用和原有疾病治愈率；不良反应发生率。其中未用药组30例，不进行SU的预防；用药组60例，使用抑酸药（ASD）预防SU。结果：未用药组与用药组均未出现术后SU和严重不良反应；二者在住院时间、住院费用、药品费用和原有疾病治愈率上的差异均无统计学意义；未用药组平均住院费用和平均药品费用均低于用药组。结论：对于不存在高危因素的LC患者，预防应激性溃疡是没有必要的。
　　목적：평개비고위인소적복강경하담낭절제술（LC）환자예방응격성궤양（SU）적필요성，위림상합리용약제공삼고。방법：장90례비고위인소적복강경하담낭절제술환자안1：2적비례수궤분위미용약조화용약조，병진행회고성분석：술후SU적발생솔；주원시간、주원비용、약품비용화원유질병치유솔；불량반응발생솔。기중미용약조30례，불진행SU적예방；용약조60례，사용억산약（ASD）예방SU。결과：미용약조여용약조균미출현술후SU화엄중불량반응；이자재주원시간、주원비용、약품비용화원유질병치유솔상적차이균무통계학의의；미용약조평균주원비용화평균약품비용균저우용약조。결론：대우불존재고위인소적LC환자，예방응격성궤양시몰유필요적。
Objective To evaluate the necessity of stress ulcer (SU) prophylaxis in laparoscopic cholecystec-tomy (LC) without risk factors. Methods A total of 90 patients were included and randomly divided into non-prophylaxis group (n=30) and prophylaxis group (n=60). Analysis indicators included SU rate;duration of hospi-talization, hospitalization cost, drug cost and the cure rate of disease; Results Both of two groups didn't appear SU and adverse reaction; There is no significant differences between two groups in duration of hospitalization, hospitalization cost, drug cost and the cure rate of disease;The non-prophylaxis group take a lower average hos-pitalization cost and drug cost than the prophylaxis group. Conclusion It is not necessary to take SU prophylaxis in Surgical Patients without Risk Factors.