中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
6期
1054-1056
,共3页
医院感染%手术切口%病原菌%耐药性
醫院感染%手術切口%病原菌%耐藥性
의원감염%수술절구%병원균%내약성
Hospital infection%Operative incision%Pathogenic bacteria%Drug resistance
目的：探讨骨科手术切口感染的病原菌分布及耐药情况，指导抗生素的合理应用并采取综合预防措施。方法：对本院2008年7月~2011年6月骨科146例手术切口感染病例的病原菌分布及耐药性进行回顾性分析。结果：146例手术切口感染标本分离出165株细菌，病原菌以革兰阴性菌为主，占63.1%；革兰阳性菌及棒状杆菌占32.1%，真菌占2.4%，病原菌呈现出多重耐药性；耐甲氧西林金黄色葡萄球菌(MRSA)分离率为37.3%；耐甲氧西林凝固酶葡萄球菌(MRCNS)分离率为43.5%；大肠埃希菌和肺炎克雷伯菌含超广谱β-内酰胺酶(ESBL)分离率分别是50.1%和38.1%。结论：骨科手术切口感染的病原菌多为多药耐药菌，临床医生应注意监测细菌变迁及耐药，注意仪器消毒灭菌，加强无菌观念，注意感染患者的隔离等均能有效的减少感染的发生。
目的：探討骨科手術切口感染的病原菌分佈及耐藥情況，指導抗生素的閤理應用併採取綜閤預防措施。方法：對本院2008年7月~2011年6月骨科146例手術切口感染病例的病原菌分佈及耐藥性進行迴顧性分析。結果：146例手術切口感染標本分離齣165株細菌，病原菌以革蘭陰性菌為主，佔63.1%；革蘭暘性菌及棒狀桿菌佔32.1%，真菌佔2.4%，病原菌呈現齣多重耐藥性；耐甲氧西林金黃色葡萄毬菌(MRSA)分離率為37.3%；耐甲氧西林凝固酶葡萄毬菌(MRCNS)分離率為43.5%；大腸埃希菌和肺炎剋雷伯菌含超廣譜β-內酰胺酶(ESBL)分離率分彆是50.1%和38.1%。結論：骨科手術切口感染的病原菌多為多藥耐藥菌，臨床醫生應註意鑑測細菌變遷及耐藥，註意儀器消毒滅菌，加彊無菌觀唸，註意感染患者的隔離等均能有效的減少感染的髮生。
목적：탐토골과수술절구감염적병원균분포급내약정황，지도항생소적합리응용병채취종합예방조시。방법：대본원2008년7월~2011년6월골과146례수술절구감염병례적병원균분포급내약성진행회고성분석。결과：146례수술절구감염표본분리출165주세균，병원균이혁란음성균위주，점63.1%；혁란양성균급봉상간균점32.1%，진균점2.4%，병원균정현출다중내약성；내갑양서림금황색포도구균(MRSA)분리솔위37.3%；내갑양서림응고매포도구균(MRCNS)분리솔위43.5%；대장애희균화폐염극뢰백균함초엄보β-내선알매(ESBL)분리솔분별시50.1%화38.1%。결론：골과수술절구감염적병원균다위다약내약균，림상의생응주의감측세균변천급내약，주의의기소독멸균，가강무균관념，주의감염환자적격리등균능유효적감소감염적발생。
Objective:To investigate pathogenic distribution and drug resistance in patients with operative incision infection in orthopedics department for the rational use of antibiotics and adopt comprehensive prevention measures in clinical work.Methods:The clinical date of 165 operative incision infection in orthopedics department were retrospectivsly analyzed from July 2008 to June 2011.Results:165 strains of incision infective bacteria were isolated from 146 cases,Most of the pathogens were Gram negative bacilli accounting for 63.1%,Gram positive bacilli and Fungus were 32.1%,2.4%.Mst pathogens exhibit multiple drug resistance,The isolative rate of MRSA and MRCNS in Staphylococcus were 37.3% and 43.5%.The isolative rate of ESBL in Escherichia coli and Klebsiella pneumoniae were 50.1% and 38.1%. Conclusion:Pathogens from infected operative incision are mostly multidrug resistance strains,Clinical doctor have to monitor distributive change and drug resistance spectrum of bacteria and choose antibiotics reasonably.Besides,paying more attention to the sterilization、strengthening the aseptic concept of medical staffs、isolating the infectious patients and enhancing the supportive treatments do make sense to prevent cross-infections.
