CAJ | 학술논문

　　目的：观察左卡尼汀注射液在舒张性心力衰竭治疗中的临床疗效。方法：选取我院2010年1月~2012年5月住院患者136例，随机分为对照组57例和治疗组79例，对照组常规给予琥珀酸美托洛尔、雷米普利、利尿剂等口服；治疗组在此治疗基础之上加用左卡尼汀注射液。比较治疗组和对照组治疗前后的心功能以及BNP、EV、AV、E/A比值、EDT和IRT各项指标。结果：治疗组无论在心功能改善上、心脏舒张功能指标和BNP测定值上均优于对照组，具有统计学意义。结论：左卡尼汀注射液明显改善舒张性心力衰竭患者临床症状和各项心脏舒张指标，优于常规治疗方法。
　　목적：관찰좌잡니정주사액재서장성심력쇠갈치료중적림상료효。방법：선취아원2010년1월~2012년5월주원환자136례，수궤분위대조조57례화치료조79례，대조조상규급여호박산미탁락이、뢰미보리、이뇨제등구복；치료조재차치료기출지상가용좌잡니정주사액。비교치료조화대조조치료전후적심공능이급BNP、EV、AV、E/A비치、EDT화IRT각항지표。결과：치료조무론재심공능개선상、심장서장공능지표화BNP측정치상균우우대조조，구유통계학의의。결론：좌잡니정주사액명현개선서장성심력쇠갈환자림상증상화각항심장서장지표，우우상규치료방법。
Objective:To observe the effects of levocarnitine in treating with diastolic dysfunction.Methods:136 patients with diastolic dysfunction were divided into the treatment group(n=79)and the control group(n=57) who were in our hospital from January 2010 to May 2012.All the patients in the both group were given metoprolol succinate,ramipril and diuretics,those patients in the treatment group were added levocarnitine injection by intravenous drip.Results:The clinical effects in the treatment group are better than those in the control group,especially on the indexes of cardiac diastolic function, and the value of BNP.Conclusion:Levocarnitine injection could more rapidly inhibit diastolic dysfunction than those routine treatments.It is safe and effective in treating diastolic dysfunction.