CAJ | 학술논문

　　目的：探讨入院时肝肾功能与NT-proBNP水平对扩张型心肌病患者预后的影响。方法：114例扩张型心肌病患者为四组，分别是扩张型心肌病伴肝肾功能不全组(A组)26例，伴肝功能不全组(B组)16例，伴肾功能不全组(C组)28例和肝肾功能正常组(D组)44例。首次入院后检测肝肾功能和血浆NT-proBNP浓度；所有患者随访并记录1年内发生的主要不良心血管事件(MACE)。结果：A组患者NT-proBNP水平、恶性心律失常发生率和总死亡率较其他三组均较显著升高(P<0.05)；D组患者MACE发生率在四组中最低(P<0.05)。结论：肝肾功能与NT-proBNP可以很好的评估扩张型心肌病患者的预后，指导临床治疗。
　　목적：탐토입원시간신공능여NT-proBNP수평대확장형심기병환자예후적영향。방법：114례확장형심기병환자위사조，분별시확장형심기병반간신공능불전조(A조)26례，반간공능불전조(B조)16례，반신공능불전조(C조)28례화간신공능정상조(D조)44례。수차입원후검측간신공능화혈장NT-proBNP농도；소유환자수방병기록1년내발생적주요불양심혈관사건(MACE)。결과：A조환자NT-proBNP수평、악성심률실상발생솔화총사망솔교기타삼조균교현저승고(P<0.05)；D조환자MACE발생솔재사조중최저(P<0.05)。결론：간신공능여NT-proBNP가이흔호적평고확장형심기병환자적예후，지도림상치료。
Objective:To investigate the effects of liver and kidney function and NT-proBNP level on patients with dilated cardiomyopathy. Methods:114 patients with dilated cardiomyopathy were divided into four groups,including dilated cardiomyopathy associated with liver and kidney dysfunction group(group A,n=26),associated with liver dysfunction group(group B,n=16),associated with kidney dysfunction group(group C,n=26) and normal liver and kidney function group(group D,n=26).Liver and kidney function and plasma NT-proBNP concentration were detected after first time adminssion.All patients were followed up and recorded major adverse cardiac events(MACE)occurred in one year.Results:The NT-proBNP level,incidence of malignant arrhythmias and total mortality in groupA were significantly higher than other three groups(P<0.05).The incidence of MACE in group D was lowest in the four groups(P<0.05).Conclusion:Liver and kidney function and NT-proBNP can better assess the prognosis of patients with dilated cardiomyopathy and guide Clinical treatment.