CAJ | 학술논문

目的：观察润肺解毒散结颗粒联合化疗治疗晚期非小细胞肺癌（NSCLC）临床疗效。方法：将162例入选患者随机分为两组。对照组GP方案治疗；治疗组在对照组治疗基础上加服润肺解毒散结颗粒。观察两组证候改善、毒副反应发生率。结果：治疗组毒副反应少于对照组，差异有显著性意义（P<0.05）；治疗组证候较对照组明显改善（P<0.05）。结论：润肺解毒散结颗粒联合化疗，对晚期NSCLC，肺阴虚证患者是有效、低毒的治疗方法，值得临床推广应用。
목적：관찰윤폐해독산결과립연합화료치료만기비소세포폐암（NSCLC）림상료효。방법：장162례입선환자수궤분위량조。대조조GP방안치료；치료조재대조조치료기출상가복윤폐해독산결과립。관찰량조증후개선、독부반응발생솔。결과：치료조독부반응소우대조조，차이유현저성의의（P<0.05）；치료조증후교대조조명현개선（P<0.05）。결론：윤폐해독산결과립연합화료，대만기NSCLC，폐음허증환자시유효、저독적치료방법，치득림상추엄응용。
Objective: To observe the clinical effect of Runfei Jiedu Sanjie granule plus chemotherapy on treating later period NSCLC. Methods:162 patients were selected and randomly divided into two groups:62 patients in the control group with chemotherapy alone (GP/NP).100 patients in the treatment group were administered with Runfei Jiedu Sanjie granule and chemotherapy (the regimen as same). Two groups were observed with main symptom improvement, adverse reactions. Results:The clinical symptoms in the treatment group were superior to those in the control group, as well as reducing adverse reactions (P<0.05). Conclusion:Runfei Jiedu Sanjie granule combined with chemotherapy can be used as an effective, low toxicity approach to treat those that later period NSCLC, and is worthy of clinical application.