广西医学
廣西醫學
엄서의학
GUANGXI MEDICAL JOURNAL
2013年
6期
665-667,680
,共4页
韦肖新%周诺%黄旋平%温结明
韋肖新%週諾%黃鏇平%溫結明
위초신%주낙%황선평%온결명
冻干骨%冷冻骨%犬下颌骨%骨生物力学性能%新鲜骨%抗压强度%抗弯强度
凍榦骨%冷凍骨%犬下頜骨%骨生物力學性能%新鮮骨%抗壓彊度%抗彎彊度
동간골%냉동골%견하합골%골생물역학성능%신선골%항압강도%항만강도
Freeze-dried bone%Frozen bone%Canine mandibular%Bone biomechanical property%Fresh bone%Anti-compressive strength%Anti-bending strength
目的探讨经冷冻和冷冻脱脂干燥处理的冷冻骨和冻干骨的生物力学性能变化，为同种异体骨移植术和牵张成骨术联合应用提供参考。方法健康杂种狗6只，取其下颌骨分为新鲜骨组Ⅰ、冷冻骨组、新鲜骨组Ⅱ、冻干骨组，每组分别进行弯曲试验、压缩试验。结果冷冻骨组最大弯曲力、抗弯强度、弯曲挠度均明显低于新鲜骨组Ⅰ（P＜0．05），弯曲弹性模量明显高于新鲜骨组Ⅰ（P＜0．05）。冻干骨组最大弯曲力、弯曲强度、弯曲挠度均明显低于新鲜组骨Ⅱ（P＜0．05），弯曲弹性模量明显高于新鲜组骨Ⅱ（P＜0．05）。冷冻骨组最大压缩力、抗压强度、压缩挠度均明显低于新鲜骨组Ⅰ（P＜0．05），压缩弹性模量明显高于新鲜骨组Ⅰ（P＜0．05），冻干骨组最大压缩力、抗压强度、压缩挠度均明显低于新鲜骨组Ⅱ（P＜0．05），压缩弹性模量明显高于新鲜骨组Ⅱ（P＜0．05）。结论与新鲜骨相比，冷冻骨和冻干骨的生物力学压缩强度，抗弯强度均依次下降，冻干骨下降更明显；而弯曲弹性模量、压缩弹性模量均依次增加。
目的探討經冷凍和冷凍脫脂榦燥處理的冷凍骨和凍榦骨的生物力學性能變化，為同種異體骨移植術和牽張成骨術聯閤應用提供參攷。方法健康雜種狗6隻，取其下頜骨分為新鮮骨組Ⅰ、冷凍骨組、新鮮骨組Ⅱ、凍榦骨組，每組分彆進行彎麯試驗、壓縮試驗。結果冷凍骨組最大彎麯力、抗彎彊度、彎麯撓度均明顯低于新鮮骨組Ⅰ（P＜0．05），彎麯彈性模量明顯高于新鮮骨組Ⅰ（P＜0．05）。凍榦骨組最大彎麯力、彎麯彊度、彎麯撓度均明顯低于新鮮組骨Ⅱ（P＜0．05），彎麯彈性模量明顯高于新鮮組骨Ⅱ（P＜0．05）。冷凍骨組最大壓縮力、抗壓彊度、壓縮撓度均明顯低于新鮮骨組Ⅰ（P＜0．05），壓縮彈性模量明顯高于新鮮骨組Ⅰ（P＜0．05），凍榦骨組最大壓縮力、抗壓彊度、壓縮撓度均明顯低于新鮮骨組Ⅱ（P＜0．05），壓縮彈性模量明顯高于新鮮骨組Ⅱ（P＜0．05）。結論與新鮮骨相比，冷凍骨和凍榦骨的生物力學壓縮彊度，抗彎彊度均依次下降，凍榦骨下降更明顯；而彎麯彈性模量、壓縮彈性模量均依次增加。
목적탐토경냉동화냉동탈지간조처리적냉동골화동간골적생물역학성능변화，위동충이체골이식술화견장성골술연합응용제공삼고。방법건강잡충구6지，취기하합골분위신선골조Ⅰ、냉동골조、신선골조Ⅱ、동간골조，매조분별진행만곡시험、압축시험。결과냉동골조최대만곡력、항만강도、만곡뇨도균명현저우신선골조Ⅰ（P＜0．05），만곡탄성모량명현고우신선골조Ⅰ（P＜0．05）。동간골조최대만곡력、만곡강도、만곡뇨도균명현저우신선조골Ⅱ（P＜0．05），만곡탄성모량명현고우신선조골Ⅱ（P＜0．05）。냉동골조최대압축력、항압강도、압축뇨도균명현저우신선골조Ⅰ（P＜0．05），압축탄성모량명현고우신선골조Ⅰ（P＜0．05），동간골조최대압축력、항압강도、압축뇨도균명현저우신선골조Ⅱ（P＜0．05），압축탄성모량명현고우신선골조Ⅱ（P＜0．05）。결론여신선골상비，냉동골화동간골적생물역학압축강도，항만강도균의차하강，동간골하강경명현；이만곡탄성모량、압축탄성모량균의차증가。
Objective To investigate the biomechanical properties of frozen bone and freeze -dried bone so as to provide the reference for combining application of allogeneic bone transplantation and distraction osteogenesis .Methods Six normal mongrel dogs were divided into fresh bone groupⅠ,frozen bone group,fresh bone groupⅡand freeze-dried bone group based on their mandibles,tension test and bending test were conducted in each group.Results The maximum bending force,anti-bending strength,bending deflection in the frozen bone group were significantly lower than those in the fresh bone group Ⅰ(P<0.05),the bending elastic modulus in the frozen bone group was significantly higher than that in the fresh bone group Ⅰ(P <0.05).The maximum bending force,anti-bending strength,bending deflection in the freeze-dried bone group were significantly lower than those in the fresh bone group Ⅱ(P<0.05),the bending elastic modulus in the freeze-dried bone group was significantly higher than that in the fresh bone group Ⅱ(P<0.05).The maximum compressive force,anti-compressive strength,compressive deflection in the frozen bone group were significantly lower than those in the fresh bone groupⅠ(P<0.05),the compressive elastic modulus in the frozen bone group was significantly higher than that in the fresh bone group Ⅰ(P <0.05).The maximum compressive force ,anti-compressive strength, compressive deflection in the freeze-dried bone group were significantly lower than those in the fresh bone group Ⅱ(P<0.05),the compressive elastic modulus in the freeze-dried bone group was significantly higher than that in the fresh bone group Ⅱ(P<0.05).Conclusion Compared with the fresh bone,the biomechanical properties of frozen bone and freeze-dried bone,such as compressive strength,anti-bending strength,decrease in turn,which decrease more significantly in the freeze-dried bone group;However,the bending elastic modulus and compressive elastic modulus increase in turn.
