中国卒中杂志
中國卒中雜誌
중국졸중잡지
CHINESE JOURNAL OF STROKE
2013年
7期
585-589
,共5页
骨髓增殖性肿瘤%缺血性卒中%血栓形成%JAK2V617F突变
骨髓增殖性腫瘤%缺血性卒中%血栓形成%JAK2V617F突變
골수증식성종류%결혈성졸중%혈전형성%JAK2V617F돌변
Myeloproliferative neoplasms%Ischemic stroke%Thrombosis%JAK2V617F mutation
骨髓增殖性肿瘤常出现血管并发症,最常累及脑血管,以缺血性卒中最为常见。骨髓增殖性肿瘤作为缺血性卒中的病因之一,其诊断与治疗不同于其他病因所致卒中。白细胞增多、JAK2V617F基因突变等相继被发现与缺血性卒中相关。本文对骨髓增殖性肿瘤伴缺血性卒中的发生、机制及防治的新进展进行综述。
骨髓增殖性腫瘤常齣現血管併髮癥,最常纍及腦血管,以缺血性卒中最為常見。骨髓增殖性腫瘤作為缺血性卒中的病因之一,其診斷與治療不同于其他病因所緻卒中。白細胞增多、JAK2V617F基因突變等相繼被髮現與缺血性卒中相關。本文對骨髓增殖性腫瘤伴缺血性卒中的髮生、機製及防治的新進展進行綜述。
골수증식성종류상출현혈관병발증,최상루급뇌혈관,이결혈성졸중최위상견。골수증식성종류작위결혈성졸중적병인지일,기진단여치료불동우기타병인소치졸중。백세포증다、JAK2V617F기인돌변등상계피발현여결혈성졸중상관。본문대골수증식성종류반결혈성졸중적발생、궤제급방치적신진전진행종술。
Myeloproliferative neoplasms (MPNs) often occur with vascular complications, most commonly involving cerebrovascular, and ischemic stroke is the most common. MPNs as a cause of ischemic stroke are different to other causes of stroke in diagnosis and treatment. And leukocytosis and JAK2V617F mutations have been found associated with ischemic stroke. In this paper, an updated overview of morbidity and pathogenesis, prevention and treatment in MPNs with ischemic stroke is presented.