CAJ | 학술논문

　　目的探讨青年与老年冠心病(coronary heart disease，CHD)患者行冠状动脉旁路移植术(coronary artery bypass grafting， CABG)手术疗效及发病危险因素。方法选择我院2009年5月-2012年5月所有单纯行CABG患者(≤45岁51例；≥65岁386例)与同期行心脏手术的非冠心病患者(≤45岁68例，≥65岁247例)。比较CHD组与非CHD组的术前因素、CHD组两个年龄段术中及术后指标、并发症及死亡率等，并进行危险因素相关分析。结果青年CHD组在呼吸机辅助时间、ICU时间及住院时间等方面明显小于老年CHD组(P＜0.05)，在男性、阳性家族史、吸烟、超重、低-高密度脂蛋白(HDL)等方面明显高于老年CHD组(P＜0.05)。结论青年CHD组手术疗效好于老年组，老年CHD组手术近期效果令人满意；青年CHD危险因素以男性、阳性家族史、吸烟、超重、低-HDL为主，应针对可控因素进行健康教育及治疗。
　　목적탐토청년여노년관심병(coronary heart disease，CHD)환자행관상동맥방로이식술(coronary artery bypass grafting， CABG)수술료효급발병위험인소。방법선택아원2009년5월-2012년5월소유단순행CABG환자(≤45세51례；≥65세386례)여동기행심장수술적비관심병환자(≤45세68례，≥65세247례)。비교CHD조여비CHD조적술전인소、CHD조량개년령단술중급술후지표、병발증급사망솔등，병진행위험인소상관분석。결과청년CHD조재호흡궤보조시간、ICU시간급주원시간등방면명현소우노년CHD조(P＜0.05)，재남성、양성가족사、흡연、초중、저-고밀도지단백(HDL)등방면명현고우노년CHD조(P＜0.05)。결론청년CHD조수술료효호우노년조，노년CHD조수술근기효과령인만의；청년CHD위험인소이남성、양성가족사、흡연、초중、저-HDL위주，응침대가공인소진행건강교육급치료。
Objective To study the outcome and risk factor for coronary heart disease (CHD) in young and elderly patients after coronary artery bypass grafting (CABG). Methods Four hundred and thirty-seven CHD patients (51 with their age≤45 years and 386 with their age≥65 years) who underwent CABG in our hospital from May 2009 to May 2012 served as a CHD group and 315 non-CHD patients (68 with their age≤45 years and 247 with their age≥65 years) who underwent heart surgery in our hospital from May 2009 to May 2012 served as a non-CHD group in this study. Risk factors for CHD before operation, intraoperative and postoperative complications and mortality were compared between the two groups and correlation between risk factors for CHD was analyzed. Results The respiratory auxiliary time, ICU and hospital stay time were significantly shorter in CHD patients with their age≤45 years than in those with their age≥65 years after CABG (P<0.05). Male, family history of CHD, smoking, high BMI, LDL and HDL were the risk factors for CHD in patients with their age≤45 years. Conclusion The outcome is better in CHD patients with their age≤45 years than in those with their age≥65 years after CABG. Male, family history of CHD, smoking, high BMI, LDL and HDL are the risk factors for CHD in patients with their age≤45 years. Such patients should be educated and treated according to their controllable factors.