CAJ | 학술논문

　　目的探讨重复应用微波高温灭活治疗股骨远端骨巨细胞瘤的临床应用效果。方法回顾性分析我科2006年6月-2012年6月采用重复应用微波高温灭活方法治疗股骨远端骨巨细胞瘤11例，男7例，女4例，年龄19~42岁，中位年龄27岁，术后自体髂骨、骨水泥修复骨缺损从手术技术、肿瘤复发情况、膝关节功能等方面全面综合评价此方法临床应用效果。结果全部患者均获得随访，平均随访时间26个月，11例均获得骨性愈合，无骨折及内固定断裂发生，1例在术后18个月局部复发；无伤口并发症及深部感染发生，无远处转移。肢体关节功能优8例、良3例。结论微波原位灭活后再行微波辅助残腔灭活，可以有效灭活术后残腔和周围肿瘤卫星灶。术后行自体髂骨、骨水泥修复骨缺损，可以早期负重活动，获得良好的关节功能锻炼，缩短疗程，从而获得优良的疗效及肢体关节功能。
　　목적탐토중복응용미파고온멸활치료고골원단골거세포류적림상응용효과。방법회고성분석아과2006년6월-2012년6월채용중복응용미파고온멸활방법치료고골원단골거세포류11례，남7례，녀4례，년령19~42세，중위년령27세，술후자체가골、골수니수복골결손종수술기술、종류복발정황、슬관절공능등방면전면종합평개차방법림상응용효과。결과전부환자균획득수방，평균수방시간26개월，11례균획득골성유합，무골절급내고정단렬발생，1례재술후18개월국부복발；무상구병발증급심부감염발생，무원처전이。지체관절공능우8례、량3례。결론미파원위멸활후재행미파보조잔강멸활，가이유효멸활술후잔강화주위종류위성조。술후행자체가골、골수니수복골결손，가이조기부중활동，획득량호적관절공능단련，축단료정，종이획득우량적료효급지체관절공능。
Objective To study the effect of repeated microwave hyperthermia inactivation on distal femur giant cell tumor. Methods Clinical data about 11 patients (7 males and 4 females) aged 19-42 years old (mean 27 years old) with distal femur giant cell tumor who underwent repeated microwave hyperthermia inactivation in our department from June 2006 to June 2012 were retrospectively analyzed. The effect of repeated microwave hyperthermia inactivation on repair of knee-cap defect with bone cement was assessed from the aspects of tumor reccurrence and knee joint function after operation. Results The patients were followed up for an average period of 26 months, during which the knee-cap was healed without fracture, internal fixation plate rupture, complication, deep infection, and distal metastasis. Local recurrence occurred in 1 patient 18 months after operation. Excellent and good functions of joints were achieved in 8 and 3 patients, respectively. Conclusion Combined in situ microwave hyperthermia inactivation and residual cavity microwave hyperthermia inactivation can effectively inactivate the residual cavity tumor and its adjacent foci, and repair the knee-cap defect with bone cement. The patients can carry out physical exercises with a heavy burden early after operation and shoten the course of treatment, thus improving their joint function.