CAJ | 학술논문

咳嗽变异性哮喘(cough variant asthma,CVA)是指以慢性咳嗽为主要或唯一症状的一种特殊类型哮喘,其病理生理改变与典型哮喘相同,若未及时诊治,约30%~40%可发展成为典型哮喘。气道炎细胞浸润和气道重塑是 CVA 的病理基础。CVA 可称之为一种隐匿性哮喘,常被临床医师所忽略,患者失去正确的诊断与治疗。正确认识 CVA 的病理生理特征,对临床诊断和治疗具有重要的指导意义,可降低典型哮喘的发病率。本文就 CVA 与气道炎性反应和气道重塑的关系作一综述。
해수변이성효천(cough variant asthma,CVA)시지이만성해수위주요혹유일증상적일충특수류형효천,기병리생리개변여전형효천상동,약미급시진치,약30%~40%가발전성위전형효천。기도염세포침윤화기도중소시 CVA 적병리기출。CVA 가칭지위일충은닉성효천,상피림상의사소홀략,환자실거정학적진단여치료。정학인식 CVA 적병리생리특정,대림상진단화치료구유중요적지도의의,가강저전형효천적발병솔。본문취 CVA 여기도염성반응화기도중소적관계작일종술。
Cough variant asthma(CVA)is a special typologic bronchial asthma (asthma)which presents solely with chronic cough.CVA is a form of asthma,CVA shares a number of pathophysiological features with classic asthma. More importantly,30% to 40% of adult patients with CVA,unless adequately treated,may progress to classic asthma. Cellular infiltration and airway remodeling are pathological basis of CVA.CVA may call an insidious asthma,it was neglected freguently by clinician,and the patients were missed correct diagnosis and treatment.To know correctly pathophysiological features of CVA,it is important significance for clinical treatment,and may decrease incidence of asthma.In this review,we analyzed the correlation between CVA and inflammatory reaction,airway remodeling.