CAJ | 학술논문

目的：通过对呼气峰速仪及肺功能仪所测出的PEF/Pred（最高呼气峰流速值/预计值）进行相关性及差异性统计学分析，探讨呼气峰速仪在支气管哮喘患者诊疗中的应用价值。方法选取2012年3月～2012年5月山西医科大学第二临床医院64例哮喘患者，分别用呼气峰速仪及肺功能仪对其进行PEF测定，计算PEF/Pred；用肺功能测出FEV 1/Pred（第1 s用力呼气量/预计值），对FEV 1/Pred＞70%的51例哮喘患者进行激发试验，对FEV 1/Pred＜70%的13例哮喘患者进行扩张试验，同时再用呼气峰速仪及肺功能仪对64例哮喘患者进行PEF测定，计算PEF/Pred；对呼气峰速仪及肺功能仪分别测出的前PEF/Pred、后PEF/Pred及PEF变异率进行相关性及差异性分析。结果呼气峰速仪及肺功能仪分别测出的前PEF/Pred明显相关（r=0.884， P＜0.01）,经配对t检验差异无统计学意义；激发试验后二者PEF/Pred明显相关（r=0.666，P＜0.01），经配对t检验差异无统计学意义；扩张试验后二者PEF/Pred明显相关（r=0.863，P＜0.01），经配对t检验差异无统计学意义。结论呼气峰速仪体积小，操作简单，价格低廉，与肺功能仪相比，体现了优越性，可应用于支气管哮喘患者，根据PEF/Pred评估气道阻塞程度，对哮喘患者诊疗起到重要指导作用。
목적：통과대호기봉속의급폐공능의소측출적PEF/Pred（최고호기봉류속치/예계치）진행상관성급차이성통계학분석，탐토호기봉속의재지기관효천환자진료중적응용개치。방법선취2012년3월～2012년5월산서의과대학제이림상의원64례효천환자，분별용호기봉속의급폐공능의대기진행PEF측정，계산PEF/Pred；용폐공능측출FEV 1/Pred（제1 s용력호기량/예계치），대FEV 1/Pred＞70%적51례효천환자진행격발시험，대FEV 1/Pred＜70%적13례효천환자진행확장시험，동시재용호기봉속의급폐공능의대64례효천환자진행PEF측정，계산PEF/Pred；대호기봉속의급폐공능의분별측출적전PEF/Pred、후PEF/Pred급PEF변이솔진행상관성급차이성분석。결과호기봉속의급폐공능의분별측출적전PEF/Pred명현상관（r=0.884， P＜0.01）,경배대t검험차이무통계학의의；격발시험후이자PEF/Pred명현상관（r=0.666，P＜0.01），경배대t검험차이무통계학의의；확장시험후이자PEF/Pred명현상관（r=0.863，P＜0.01），경배대t검험차이무통계학의의。결론호기봉속의체적소，조작간단，개격저렴，여폐공능의상비，체현료우월성，가응용우지기관효천환자，근거PEF/Pred평고기도조새정도，대효천환자진료기도중요지도작용。
Objective To investigate the value of the expiratory peak flow meter in the diagnosis and the treatment of patients with bronchial asthma by performing both correlation analysis and difference analysis of the PEF/Pred(peak expiratory flow/predicted value)measured with the expiratory peak flow meter and the spirometer respectively.Methods (1)64 patients with bronchial asthma were randomly selected. The PEF was measured with the expiratory peak flow meter and the spirometer respectively, based on which the PEF/Pred was calculated;(2)the FEV 1/Pred(forced expiratory volume in 1 s/predicted value)was measured with the spirometer. A bronchial provocation test was carried out on the 51 patients whose FEV 1/Pred was above 70%, while a dilation test was carried out on the other 13 patients whose FEV 1/Pred was below 70%. Then the PEF of all the 64 patients were measured with both the expiratory peak flow meter and the spirometer again. The PEF/Pred were calculated;(3) correlation analysis and difference analysis were made between the pre-PEF/Pred, the post-PEF%Pred ,which were measured with the expiratory peak flow meter and the spirometer respectively. Results (1)The pre-PEF/Pred measured with the expiratory peak flow meter and that with the spirometer were significantly related (r=0.884, P<0.01), the Paired Samples Test indicated no statistical significance; (2) After the provocation test, the two PEF/Preds were significantly related(r=0.666,P<0.01), the Paired Samples Test indicated no statistical significance;(3) After the dilation test, the two PEF/Preds were significantly related(r=0.863,P<0.01), the Paired Samples Test indicated no statistical significance. Conclusion The expiratory peak flow meter, small in size and easy to operate, can be applied into the measurement of the lung function of the patients with bronchial asthma. The PEF/Pred used to assess the extent to the degree of airway obstruction plays a prominent role in the diagnosis and the treatment of the asthma patients.