CAJ | 학술논문

　　目的?研究分析不同血脂指标对于我国中年人群缺血性心血管疾病事件的预测作用。方法选择住院、门诊、社区及体检人群资料完整的10200人作为研究对象。所有被研究者的平均随访时间为（15.8±2.1）年。观察缺血性心血管疾病事件，其包括冠心病以及缺血性脑卒中。结果在随访期间出现缺血性心血管疾病（ICVD）事件有372例，其中单纯冠心病94例，缺血性脑卒中267例，冠心病合并缺血性脑卒中11例。人群血清总胆固醇水平与ICVD发病呈现出正相关关系，但是HDL-C水平与ICVD发病有负相关关系，但没有统计学意义。结论我国中年人群的血脂水平明显低于西方人群，血清TC、LDL-C以及NHDL-C以及TC/HDL-C水平升高对于ICVD发病具有独立预测的作用，控制血脂在正常的水平下可以有效减少人群中ICVD的发病率，具有比较重要的意义。
　　목적?연구분석불동혈지지표대우아국중년인군결혈성심혈관질병사건적예측작용。방법선택주원、문진、사구급체검인군자료완정적10200인작위연구대상。소유피연구자적평균수방시간위（15.8±2.1）년。관찰결혈성심혈관질병사건，기포괄관심병이급결혈성뇌졸중。결과재수방기간출현결혈성심혈관질병（ICVD）사건유372례，기중단순관심병94례，결혈성뇌졸중267례，관심병합병결혈성뇌졸중11례。인군혈청총담고순수평여ICVD발병정현출정상관관계，단시HDL-C수평여ICVD발병유부상관관계，단몰유통계학의의。결론아국중년인군적혈지수평명현저우서방인군，혈청TC、LDL-C이급NHDL-C이급TC/HDL-C수평승고대우ICVD발병구유독립예측적작용，공제혈지재정상적수평하가이유효감소인군중ICVD적발병솔，구유비교중요적의의。
Objective To study the analysis of different lipids index for prediction function in middle-aged Chinese ischemic cardiovascular events. Methods The heart and lung disease epidemiology research data of population 10200 people as the research object, all the mean follow-up time was researchers for (15.8±2.1) years. To observe the event of ischemic cardiovascular diseases, including coronary heart disease and ischemic stroke. Results The emergence of ischemic cardiovascular disease during the follow-up period ( ICVD ) events in 372 cases, only 94 cases of coronary heart disease, 267 cases were ischemic stroke, coronary heart disease and ischemic stroke in 11 cases. Serum total cholesterol levels and the pathogenesis of ICVD showed a positive correlation, but a negative correlation between HDL-C levels and the pathogenesis of ICVD, but no statistical significance. Conclusion The serum lipid levels in middle-aged Chinese was significantly lower than that of Western populations, elevated serum levels of TC, LDL-C and NHDL-C and TC/HDL-C level is independently predictive role in the pathogenesis of ICVD, lipid control can effectively reduce the incidence rate of ICVD in normal level, has important significance.