中国肝脏病杂志（电子版）
中國肝髒病雜誌（電子版）
중국간장병잡지（전자판）
CHINESE JOURNAL OF LIVER DISEASES(ELECTRONIC VERSION)
2013年
2期
35-38
,共4页
程丹颖%邢卉春%王笑梅%欧蔚妮%段英%赵莹莹
程丹穎%邢卉春%王笑梅%歐蔚妮%段英%趙瑩瑩
정단영%형훼춘%왕소매%구위니%단영%조형형
肝炎病毒%临床特征%肝炎,乙型%肝炎,戊型
肝炎病毒%臨床特徵%肝炎,乙型%肝炎,戊型
간염병독%림상특정%간염,을형%간염,무형
Hepatitis virus%Clinical characteristics%Hepatitis B%Hepatitis E
目的观察和分析急性病毒性肝炎（AVH）患者的临床特征。方法回顾性分析2012年1月至2013年3月本科室收治的54例AVH患者的临床资料及生物化学指标。结果54例患者中，男性31例，女性23例，男女比例为1.35︰1，平均年龄（43.85±15.95）岁。根据病原分布，分为急性乙型肝炎（AHB）组（29例，53.70%）、急性戊型肝炎（AHE）组（18例，33.33%）、未分型肝炎组（6例，11.11%）、乙型肝炎肝硬化基础上重叠戊型肝炎病毒感染组（1例，1.85%）。AHB组患者中有3例为妊娠期女性。AHB组[（37.76±13.67）岁]发病年龄低于AHE组[（54.11±13.97）岁]，差异有显著统计学意义（P ＜0.01）。血清白蛋白（ALB）水平方面，AHB组[（37.24±3.68）g/L]患者较AHE组[（33.73±4.61）g/L]高，差异有显著统计学意义（P ＜0.01）。AHB、AHE两组患者的性别比、血清丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）、总胆红素（TBil）、γ-谷氨酰转移酶（γ-GT）、碱性磷酸酶（AKP）、总胆汁酸（TBA）、胆碱酯酶（CHE）水平及住院时间，差异均无统计学意义（P均＞0.05）。结论 AHB、AHE是目前常见的AVH类型，AVH预后良好。妊娠合并AHB需引起注意。AHB多见于中青年，AHE多见于中老年。AHB患者血清ALB水平高于AHE患者。
目的觀察和分析急性病毒性肝炎（AVH）患者的臨床特徵。方法迴顧性分析2012年1月至2013年3月本科室收治的54例AVH患者的臨床資料及生物化學指標。結果54例患者中，男性31例，女性23例，男女比例為1.35︰1，平均年齡（43.85±15.95）歲。根據病原分佈，分為急性乙型肝炎（AHB）組（29例，53.70%）、急性戊型肝炎（AHE）組（18例，33.33%）、未分型肝炎組（6例，11.11%）、乙型肝炎肝硬化基礎上重疊戊型肝炎病毒感染組（1例，1.85%）。AHB組患者中有3例為妊娠期女性。AHB組[（37.76±13.67）歲]髮病年齡低于AHE組[（54.11±13.97）歲]，差異有顯著統計學意義（P ＜0.01）。血清白蛋白（ALB）水平方麵，AHB組[（37.24±3.68）g/L]患者較AHE組[（33.73±4.61）g/L]高，差異有顯著統計學意義（P ＜0.01）。AHB、AHE兩組患者的性彆比、血清丙氨痠氨基轉移酶（ALT）、天門鼕氨痠氨基轉移酶（AST）、總膽紅素（TBil）、γ-穀氨酰轉移酶（γ-GT）、堿性燐痠酶（AKP）、總膽汁痠（TBA）、膽堿酯酶（CHE）水平及住院時間，差異均無統計學意義（P均＞0.05）。結論 AHB、AHE是目前常見的AVH類型，AVH預後良好。妊娠閤併AHB需引起註意。AHB多見于中青年，AHE多見于中老年。AHB患者血清ALB水平高于AHE患者。
목적관찰화분석급성병독성간염（AVH）환자적림상특정。방법회고성분석2012년1월지2013년3월본과실수치적54례AVH환자적림상자료급생물화학지표。결과54례환자중，남성31례，녀성23례，남녀비례위1.35︰1，평균년령（43.85±15.95）세。근거병원분포，분위급성을형간염（AHB）조（29례，53.70%）、급성무형간염（AHE）조（18례，33.33%）、미분형간염조（6례，11.11%）、을형간염간경화기출상중첩무형간염병독감염조（1례，1.85%）。AHB조환자중유3례위임신기녀성。AHB조[（37.76±13.67）세]발병년령저우AHE조[（54.11±13.97）세]，차이유현저통계학의의（P ＜0.01）。혈청백단백（ALB）수평방면，AHB조[（37.24±3.68）g/L]환자교AHE조[（33.73±4.61）g/L]고，차이유현저통계학의의（P ＜0.01）。AHB、AHE량조환자적성별비、혈청병안산안기전이매（ALT）、천문동안산안기전이매（AST）、총담홍소（TBil）、γ-곡안선전이매（γ-GT）、감성린산매（AKP）、총담즙산（TBA）、담감지매（CHE）수평급주원시간，차이균무통계학의의（P균＞0.05）。결론 AHB、AHE시목전상견적AVH류형，AVH예후량호。임신합병AHB수인기주의。AHB다견우중청년，AHE다견우중노년。AHB환자혈청ALB수평고우AHE환자。
Objective To investigate and analyze clinical characteristics of patients with acute viral hepatitis. Methods Data of 54 cases with acute viral hepatitis in our department from January 2012 to March 2013 were analyzed by descriptive method. Results Among 54 cases with acute viral hepatitis, 31 cases were male and 23 cases were female, with the ratio of male/female as 1.35︰1, and the mean age was (43.85 ± 15.95) years old. The results showed that 29 (53.70%) cases were acute hepatitis B (AHB), 18 (33.33%) cases with acute hepatitis E (AHE), 6 (11.11%) cases with undifferentiated type hepatitis and 1 (1.85%) cases with AHE complicated with cirrhosis based on hepatitis B. There were 3 pregnant women in AHB group. The average age of onset of AHB [(37.76 ± 13.67) years old] was lower than that of AHE [(54.11 ± 13.97) years old], and the difference was statistically significant (P < 0.01). The level of albumin (ALB) of AHB [(37.24 ± 3.68) g/L] was higher than that of AHE [(33.73 ± 4.61) g/L]. The difference of ALB between the two groups was significant (P < 0.01). There were no significant difference in sex ratio and peak values of alanine aminotransferase (ALT), aspartate amino transferase (AST), total bilirubin (TBil), γ-glutamyltransferase (γ-GT), alkaline phosphatase (AKP), total bile acid (TBA) and cholinesterase (CHE) between AHB and AHE group (all P > 0.05). The difference of course of hospital stay between the two groups were not significant (P > 0.05). Conclusions AHB and AHE were the common types of AVH. The prognosis of AVH is favorable. We should pay more attention to pregnancy women who were complicated with AHB. AHB was more common in youngers and middle-aged, while AHE more common in the elders. And serum levels of ALB was higher for patients with AHB than AHE.
