CAJ | 학술논문

　　利用电感耦合等离子体-质谱仪（ICP-MS）测定板蓝根原药材和水煎液中13种元素的含量。形态研究采用高速离心和滤膜分离水煎液中的溶解态和颗粒态，元素的溶解态再用树脂XAD-4、树脂D001、树脂D301和树脂D751分别区分非极性吸附态、阳离子交换态、阴离子交换态和螯合吸附态。结果表明，板蓝根药材含有微量Cu、Pb和Cd等重金属，同时含有丰富的Mg、Ca、Fe、Al等大量元素，其中Ca含量最高，为2739 mg·kg-1；Zn、Mg、Ca、Mn、Al和Fe的浸出率较高，在42.9%到81.9%之间；Pb和Cu的浸出率最低，只有10%左右。Zn、Mg、Ca、Mn和Pb元素颗粒态比例在0%到9.3%之间，其他元素颗粒态比例在14.3%到85.7%之间。在溶解态当中，所有元素都具有阴离子交换态；Cu、Sn、Cr和Al没有或者很少有阳离子交换态，其余元素的阳离子交换态在32.4%到98.3之间；Al、Fe、Cu、Cr和Sn没有或者很少螯合吸附态，其余元素在54.9%到98.4%之间；Zn、Cu、Sn、Cd和Pb有非极性吸附态，其余元素没有。
　　이용전감우합등리자체-질보의（ICP-MS）측정판람근원약재화수전액중13충원소적함량。형태연구채용고속리심화려막분리수전액중적용해태화과립태，원소적용해태재용수지XAD-4、수지D001、수지D301화수지D751분별구분비겁성흡부태、양리자교환태、음리자교환태화오합흡부태。결과표명，판람근약재함유미량Cu、Pb화Cd등중금속，동시함유봉부적Mg、Ca、Fe、Al등대량원소，기중Ca함량최고，위2739 mg·kg-1；Zn、Mg、Ca、Mn、Al화Fe적침출솔교고，재42.9%도81.9%지간；Pb화Cu적침출솔최저，지유10%좌우。Zn、Mg、Ca、Mn화Pb원소과립태비례재0%도9.3%지간，기타원소과립태비례재14.3%도85.7%지간。재용해태당중，소유원소도구유음리자교환태；Cu、Sn、Cr화Al몰유혹자흔소유양리자교환태，기여원소적양리자교환태재32.4%도98.3지간；Al、Fe、Cu、Cr화Sn몰유혹자흔소오합흡부태，기여원소재54.9%도98.4%지간；Zn、Cu、Sn、Cd화Pb유비겁성흡부태，기여원소몰유。
ICP-MS was employed to determine the contents of 13 elements in both the medicinal dry roots and the decoction of Radix Isatidis. Separation of the soluble and suspension portions of these metals in the decoction was achieved by high speed centrifugation and membrane filtration. The soluble decoction was further fractionized into the non-polar adsorption species, the cation adsorption species, the anion adsorption species and the chelating adsorption species with resins XAD-4, D001, D301 and D751, respectively. The results show that medicine Radix Isatidis was rich in elements such as Mg, Ca, Fe and Al, calcium content in the roots was the highest with a concentration of 2 739 mg·kg-1. The roots also contained trace amounts of heavy metals such as Cu, Pb and Cd. For Zn, Mg, Ca, Mn, Al and Fe, their rates of releasing from the roots were relatively high, ranging from 42.9% to 81.9%. Lowest releasing rates of about 10% were observed with Pb and Cu. The suspension species of Zn, Mg, Ca, Mn and Pb were measured, ranging from 0% to 9.3% of their total amounts in the decotion. For other elements, the suspension portions made up 14.3% to 85.7% of the total. In the soluble fraction of the decoction, all elements had some anion adsorption species. Cu, Sn, Cr and Al possessed no or little cation adsorption species, while other elements displayed higher proportion of cation adsorption species, ranging from 32.4% to 98.3%. Al, Fe, Cu, Cr and Sn have no or little chelating adsorption species, but for other elements, the percentage was in the range of 54.9% to 98.4%. Apparently, only Zn, Cu, Sn, Cd and Pb tended to have some non-polar adsorption species while others elements had none of them.