CAJ | 학술논문

目的探讨采用奥氮平治疗精神分裂症患者时护理干预对奥氮平致代谢综合征的影响.方法将单用奥氮平治疗的首发精神分裂症患者100例,随机分为干预组和对照组各50例.对照组进行常规精神病护理,干预组增加预防代谢综合征的护理干预措施.分别在入院当日及入院后第4、8、12、48周比较2组体重指数、空腹血糖、三酰甘油、胆固醇、高密度脂蛋白的变化.结果干预组在第4周体重指数与空腹血糖、三酰甘油、胆固醇显著低于对照组,高密度脂蛋白高于对照组.结论加强护理干预措施,可以有效控制奥氮平治疗引起的代谢综合征,以提高患者服药依从性,预防精神分裂症复发.
목적 탐토채용오담평치료정신분렬증환자시호리간예대오담평치대사종합정적영향.방법 장단용오담평치료적수발정신분렬증환자100례,수궤분위간예조화대조조각50례.대조조진행상규정신병호리,간예조증가예방대사종합정적호리간예조시.분별재입원당일급입원후제4、8、12、48주비교2조체중지수、공복혈당、삼선감유、담고순、고밀도지단백적변화.결과 간예조재제4주체중지수여공복혈당、삼선감유、담고순현저저우대조조,고밀도지단백고우대조조.결론 가강호리간예조시,가이유효공제오담평치료인기적대사종합정,이제고환자복약의종성,예방정신분렬증복발.
Objective To study the influence of nursing intervention on metabolic syndrome of schizophrenia patients treated with Olanzapine.Methods 100 acute-episode schizophrenia patients treated with Olanzapine alone were randomized into the intervention group and the control group,each group with 50 cases.The control group received the routine psychiatric nursing,and the intervention group added nursing intervention to prevent metabolic syndrome.The changes of BMI,fasting blood-glucose,triglyceride,cholesterol,high-density lipoprotein of both groups were compared on the day upon admission and on the 4th,8th,12th and 48th weeks after hospitalization respectively.Results On the 4th week BMI and fasting blood-glucose,triglyceride,cholesterol of the intervention group were significantly lower than those of the control group,but high-density lipoprotein was higher than the control group.Conclusions Strengthening nursing intervention measures can effectively control metabolic syndrome caused by Olanzapine treatment,which can improve the medication compliance of patients and prevent schizophrenia recurrence.