中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
11期
1209-1211
,共3页
何海填%李益坚%王荫槐%易路
何海填%李益堅%王蔭槐%易路
하해전%리익견%왕음괴%역로
多沙唑嗪%膀胱疾病%经尿道前列腺切除术
多沙唑嗪%膀胱疾病%經尿道前列腺切除術
다사서진%방광질병%경뇨도전렬선절제술
Doxazosin%Urinary bladder diseases%Transurethral resection of prostate
目的 观察多沙唑嗪联合双氯芬酸钠栓剂治疗前列腺等离子电切术后膀胱痉挛的效果. 方法 采用随机对照单盲临床实验设计,将入选的200例经尿道前列腺等离子电切术术后患者随机分为4组.A组(50例)于手术后即刻肛门塞双氯芬酸钠栓剂100 mg,每12h1次,麻醉清醒后口服多沙唑嗪4 mg/d;B组(50例)术后即刻肛门塞双氯芬酸钠栓剂100 mg,每12h1次;C组(50例)术后麻醉清醒后口服多沙唑嗪4 mg/d;D组(50例)术后不予预防性应用双氯芬酸钠栓剂及多沙唑嗪,均为手术后3d停药. 结果 A组术后每天平均膀胱痉挛次数[第1天:(0.47±0.18)次;第2天:(0.35±0.16)次;第3天:(0.30±0.20)次]、膀胱痉挛平均持续时间[第1天:(3.2±1.5)min;第2天:(2.1±1.3)min;第3天:(1.4±1.2)min]、膀胱持续冲洗液转淡时间(1.5±0.3)d、拔除导尿管时间(4.0±0.5)d与D组比较均少和短,均P＜0.05.B组、C组的各组分别与D组相比较也均少和短,均P＜0.05. 结论 多沙唑嗪联合双氯芬酸钠栓剂治疗前列腺等离子电切术后膀胱痉挛具有良好的效果.
目的 觀察多沙唑嗪聯閤雙氯芬痠鈉栓劑治療前列腺等離子電切術後膀胱痙攣的效果. 方法 採用隨機對照單盲臨床實驗設計,將入選的200例經尿道前列腺等離子電切術術後患者隨機分為4組.A組(50例)于手術後即刻肛門塞雙氯芬痠鈉栓劑100 mg,每12h1次,痳醉清醒後口服多沙唑嗪4 mg/d;B組(50例)術後即刻肛門塞雙氯芬痠鈉栓劑100 mg,每12h1次;C組(50例)術後痳醉清醒後口服多沙唑嗪4 mg/d;D組(50例)術後不予預防性應用雙氯芬痠鈉栓劑及多沙唑嗪,均為手術後3d停藥. 結果 A組術後每天平均膀胱痙攣次數[第1天:(0.47±0.18)次;第2天:(0.35±0.16)次;第3天:(0.30±0.20)次]、膀胱痙攣平均持續時間[第1天:(3.2±1.5)min;第2天:(2.1±1.3)min;第3天:(1.4±1.2)min]、膀胱持續遲洗液轉淡時間(1.5±0.3)d、拔除導尿管時間(4.0±0.5)d與D組比較均少和短,均P＜0.05.B組、C組的各組分彆與D組相比較也均少和短,均P＜0.05. 結論 多沙唑嗪聯閤雙氯芬痠鈉栓劑治療前列腺等離子電切術後膀胱痙攣具有良好的效果.
목적 관찰다사서진연합쌍록분산납전제치료전렬선등리자전절술후방광경련적효과. 방법 채용수궤대조단맹림상실험설계,장입선적200례경뇨도전렬선등리자전절술술후환자수궤분위4조.A조(50례)우수술후즉각항문새쌍록분산납전제100 mg,매12h1차,마취청성후구복다사서진4 mg/d;B조(50례)술후즉각항문새쌍록분산납전제100 mg,매12h1차;C조(50례)술후마취청성후구복다사서진4 mg/d;D조(50례)술후불여예방성응용쌍록분산납전제급다사서진,균위수술후3d정약. 결과 A조술후매천평균방광경련차수[제1천:(0.47±0.18)차;제2천:(0.35±0.16)차;제3천:(0.30±0.20)차]、방광경련평균지속시간[제1천:(3.2±1.5)min;제2천:(2.1±1.3)min;제3천:(1.4±1.2)min]、방광지속충세액전담시간(1.5±0.3)d、발제도뇨관시간(4.0±0.5)d여D조비교균소화단,균P＜0.05.B조、C조적각조분별여D조상비교야균소화단,균P＜0.05. 결론 다사서진연합쌍록분산납전제치료전렬선등리자전절술후방광경련구유량호적효과.
Objective To observe the clinical effect of doxazosin combined with diclofenac sodium in the treatment of bladder spasm after transurethral bipolar plasmakinetic prostatectomy (TUPKP).Methods 200 BPH patients undergoing TUPKP were randomly divided into 4 groups according to single-blind randomized controlled trial design:group A,group B,group C,group D (n =50,each).Patients in group A were given diclofenac sodium 100 mg,q12h,in anus after surgery and doxazosin 4 mg/d orally after anesthetic awareness.Patients in group B were given diclofenac sodium in anus 100 mg,q 12h in anus after surgery.Patients in group C were given doxazosin 4 mg/d orally after anesthetic awareness.Patients in group D were not given diclofenac sodium and doxazosin.Drugs were withdrawn 3 days after surgery.Results In group A,the average time of bladder spasm was (0.47±0.18) time,(0.35±0.16) time,(0.30±0.20) time at the 1st,2 nd,3 rd day respectively; the duration of bladder spasm was (3.2±1.5) min,(2.1±1.3) min,(1.4±1.2)min at the 1st,2nd,3th day respectively; the time of bladder perfusion clearance was (1.5± 0.3)days and the time of urethral catheter removal was (4.0±0.5) days.There were significant differences in above observed values between group D and the other groups (all P＜0.05).Conclusions Doxazosin combined with diclofenac sodium therapy is effective in the treatment of bladder spasm after bipolar transurethral plasmakinetic prostatectomy.
