CAJ | 학술논문

目的：探讨晨峰血压（MBPS）与动脉粥样硬化相关炎症因子的相关性。方法将116例老年高血压病患者分为 MBPS 正常组（n =56）和 MBPS 异常组（n =60），测定患者动态血压及血浆动脉粥样硬化炎症因子水平，之后分析晨峰血压水平与各炎症因子之间的相关性。结果老年高血压病患者 MBPS 除与 BMI、TC、TG 、HDL-C 等心血管危险因素相关外，MBPS 与血清 hs-CRP、TNF-α、MCP-1、MIF 水平呈正相关。结论晨峰血压除与年龄、BMI、TC、TG、HDL-C 等传统危险因素相关外，与血浆 hs-CRP、TNF-α、MCP-1、MIF 等动脉粥样硬化炎症因子也具有明显相关性。
목적：탐토신봉혈압（MBPS）여동맥죽양경화상관염증인자적상관성。방법장116례노년고혈압병환자분위 MBPS 정상조（n =56）화 MBPS 이상조（n =60），측정환자동태혈압급혈장동맥죽양경화염증인자수평，지후분석신봉혈압수평여각염증인자지간적상관성。결과노년고혈압병환자 MBPS 제여 BMI、TC、TG 、HDL-C 등심혈관위험인소상관외，MBPS 여혈청 hs-CRP、TNF-α、MCP-1、MIF 수평정정상관。결론신봉혈압제여년령、BMI、TC、TG、HDL-C 등전통위험인소상관외，여혈장 hs-CRP、TNF-α、MCP-1、MIF 등동맥죽양경화염증인자야구유명현상관성。
Objective To investigate into the correlation between morning blood pressure peak(MBPS)and athero-sclerosis related inflammatory factors in elderly patients with hypertension. Methods 116 cases of elderly hypertension were divided into MBPS normal group(n = 56)and MBPS abnormal group(n = 60),measuring blood pressure variability and ath-erosclerosis related inflammatory factors in patients respectively. Then making an analysis of the relationship between morning blood pressure peak and atherosclerosis related inflammatory factors. Results In addition to age,BMI,TC,TG,HDL-C,MBPS was positively correlated with hs CRP、-TNF-α、MCP-1、MIF. Conclusion For elderly hypertensive patients,besides age, BMI,TC,TG,HDL-C,MBPS was positively correlated with atherosclerosis related inflammatory factors such as hs CRP、-TNF-α、MCP-1、MIF.