CAJ | 학술논문

目的：讨论妊娠期糖尿病(GDM)患者糖化血红蛋白(HbA1C)和超敏 C 反应蛋白(hs-CRP)联合检测的临床意义。方法：收治GDM孕产妇130例，选择同期无其他合并症的健康孕妇130例作为对照组。对各组研究对象空腹血清中的超敏C反应蛋白和糖化血红蛋白的含量进行测定，并对各数据进行统计分析。结果：GDM组的HbA1C及hs-CRP水平均显著高于对照组，两组比较差异有统计学意义(P＜0.01)。GDM组在妊娠期高血压疾病、羊水过多明显高于对照组，比较差异均有统计学意义(P＜0.05)。结论：联合检测HbA1C及hs-CRP水平有利于GDM的早期诊断，为评价患者病情、预后及指导治疗等提供了重要的参考价值。
목적：토론임신기당뇨병(GDM)환자당화혈홍단백(HbA1C)화초민 C 반응단백(hs-CRP)연합검측적림상의의。방법：수치GDM잉산부130례，선택동기무기타합병증적건강잉부130례작위대조조。대각조연구대상공복혈청중적초민C반응단백화당화혈홍단백적함량진행측정，병대각수거진행통계분석。결과：GDM조적HbA1C급hs-CRP수평균현저고우대조조，량조비교차이유통계학의의(P＜0.01)。GDM조재임신기고혈압질병、양수과다명현고우대조조，비교차이균유통계학의의(P＜0.05)。결론：연합검측HbA1C급hs-CRP수평유리우GDM적조기진단，위평개환자병정、예후급지도치료등제공료중요적삼고개치。
Objective:To explore the clinical value of high sensitivity C reactive protein and glycosylated hemoglobin test in gestational diabetes mellitus patients.Methods:130 pregnant women with GDM were selected,130 healthy pregnant women without other complications were selected during the same period as the control group.We measured the content of high sensitive C reactive protein and glycated hemoglobin of fasting serum in each research object,and the data were statistically analyzed.Results:HbA1C and hs-CRP levels in GDM group were significantly higher than those in the control group,there was significant difference between two groups(P<0.01).The hypertensive disorders in pregnancy and polyhydramnios of GDM group were significantly higher than the control group,there was statistically significant difference(P<0.05).Conclusion:Combined detection of HbA1C and hs-CRP levels is favorable for the early diagnosis of GDM,it can provide an important reference value to evaluate the condition and prognosis and guide the treatment of patients.