CAJ | 학술논문

　　目的研究伽玛刀治疗听神经鞘瘤的疗效和并发症。方法对2003年9月至2009年8月间89例患者进行伽玛刀治疗。采用Leksell C型伽玛刀。肿瘤平均体积6.3cm3(0.75~18.2cm3)。伽玛刀治疗处方剂量为23～32Gy，40%~60%的等剂量线包绕。结果随访89例，随访24～71个月（平均51个月）。肿瘤体积明显皱缩51例（57.3%），31例肿瘤体积无明显变化（34.8%），7例肿瘤继续增大（7.9%），肿瘤生长控制率92.1%（82/89）。出现听力下降15例（16.7%），出现患侧一过性面瘫5例(5.6%)，永久面瘫率0.0%。结论伽玛刀治疗听神经鞘瘤安全有效，对面听神经及三叉神经功能有明显保留作用。是治疗术后残留、中小型体积及不能耐受手术听神经鞘瘤的有效方法之一。
　　목적연구가마도치료은신경초류적료효화병발증。방법대2003년9월지2009년8월간89례환자진행가마도치료。채용Leksell C형가마도。종류평균체적6.3cm3(0.75~18.2cm3)。가마도치료처방제량위23～32Gy，40%~60%적등제량선포요。결과수방89례，수방24～71개월（평균51개월）。종류체적명현추축51례（57.3%），31례종류체적무명현변화（34.8%），7례종류계속증대（7.9%），종류생장공제솔92.1%（82/89）。출현은력하강15례（16.7%），출현환측일과성면탄5례(5.6%)，영구면탄솔0.0%。결론가마도치료은신경초류안전유효，대면은신경급삼차신경공능유명현보류작용。시치료술후잔류、중소형체적급불능내수수술은신경초류적유효방법지일。
Objective To estimate the effects and complications of Gamma knife to acoustic neuromas. Methods Between September 2003 and August 2009, 89 patients with acoustic neuromas were treated with Gamma Knife. Use Leksell-C Gamma Knife radiosurgery. The mean tumor volume was 6.3cm3(ranging from 0.75to 18.2 cm3). The prescribed doses of the treatments were 23~32Gy.with 40%-60%isodose curves. Results 89 patients were followed up for 24 to 71 months with mean term of 51 months. The tumour shrunk in 51 cases(57.3%), stayed in the same in 31 cases(34.8%), recurrent in 7 cases(7.9%),The control rate of tumour growth was 92.1%(82/89). hearing deterioration in 15 cases(16.7%), 5 cases(5.6%) showed transient facial paralysis, the rate of permanent facial paralysis was 0.0%. Conclusion Treatment of acoustic neuromas with Gamma knife is effective and safe methods,and could prevent cranial nerve from injury to a great extent.It is one of the best treatment for postoperative tumor residual, small and middle-size acoustic neuromas,or for patients who are not suitable for craniotomy.