CAJ | 학술논문

　　目的分析脊柱多发性骨髓瘤的诊断方法和治疗效果。方法选取我院收治的多发性骨髓瘤患者，将所有患者随机分为2组，观察组30例给予改良VAD化疗方案，对照组30例给予标准的VAD化疗方案，比较两组患者的治疗效果和不良反应的发生情况。结果观察组患者与对照组患者治疗后骨痛患者的情况及M蛋白和浆细胞下降的程度没有明显差别，P>0.05；观察组患者治疗后恶心呕吐、感染和一次性高血糖的发生比例明显低于对照组，P<0.05，差异具有统计学意义，两组患者水肿的发生比例没有显著差异。结论改良后的VAD化疗方案能明显提高患者的治疗有效率和降低不良反应的发生率。
　　목적분석척주다발성골수류적진단방법화치료효과。방법선취아원수치적다발성골수류환자，장소유환자수궤분위2조，관찰조30례급여개량VAD화료방안，대조조30례급여표준적VAD화료방안，비교량조환자적치료효과화불량반응적발생정황。결과관찰조환자여대조조환자치료후골통환자적정황급M단백화장세포하강적정도몰유명현차별，P>0.05；관찰조환자치료후악심구토、감염화일차성고혈당적발생비례명현저우대조조，P<0.05，차이구유통계학의의，량조환자수종적발생비례몰유현저차이。결론개량후적VAD화료방안능명현제고환자적치료유효솔화강저불량반응적발생솔。
Objective To investigate the diagnosis and treatment protocols for spinal multiple myeloma.Methods Selected 60 cases of multiple myeloma patients , all the cases were divied into 2 groups ,the Observation group(30cases)were treated with modiifed VAD chemotherapy scheme, he control group 30 cases were given standard VAD chemotherapy regimens, compare the curative effect of two groups of patients and the occurrence of adverse reactions. Results After treatment in patients with bone pain in patients and the degree of M protein and plasma cells down in there was no signiifcant difference, P>0.05, Observation group of patients after treatment of nausea and vomiting, infection and one-time hyperglycemia ratio is signiifcantly lower than the control group, P<0.05, the difference is statistically signiifcant, the occurrence of two groups of patients with edema ratio did not differ signiifcantly. Conclusion Modiifed VAD chemotherapy can signiifcantly improve the treatment of patients with efifcient and reduce the incidence of adverse reactions.