CAJ | 학술논문

　　目的分析使用氨氯地平阿托伐他汀钙片对高血压合并冠心病进行治疗的效果。方法选取我院在2010年5月至2012年5月期间收治的高血压合并冠心病患者98例，并随机将患者分为两组，观察组的50例采取口服氨氯地平阿托伐他汀钙片的方法进行治疗，对照组的48例患者则采取口服氨氯地平片和阿托伐他汀钙片的方法进行治疗，然后对两组患者在治疗前后血压和血脂的变化进行观察和对比。结果两组患者在治疗前后血脂的各项指标以及舒张压、收缩压都有所降低，且两组之间有显著性差异（P＜0.05）；观察组的患者在治疗的舒张压、收缩压以及血脂的各项指标都明显比对照组低（P＜0.05）。两组患者的肝肾功能以及血尿常规在治疗前后的差异没有统计学意义（P＞0.05）。观察组中在治疗时有1例出现恶心现象，但是通过哟观察激酸肌酶以及肝酶，没有异常，继续进行治疗；对照组中在治疗时有3例出现心慌症状，但是程度在耐受范围之内，继续治疗之后症状好转。结论采用氨氯地平阿托伐他汀钙片对高血压合并冠心病进行治疗有非常好的临床疗效，可以明显改善患者的血脂和血压水平，值得在临床上进行推广。
　　목적분석사용안록지평아탁벌타정개편대고혈압합병관심병진행치료적효과。방법선취아원재2010년5월지2012년5월기간수치적고혈압합병관심병환자98례，병수궤장환자분위량조，관찰조적50례채취구복안록지평아탁벌타정개편적방법진행치료，대조조적48례환자칙채취구복안록지평편화아탁벌타정개편적방법진행치료，연후대량조환자재치료전후혈압화혈지적변화진행관찰화대비。결과량조환자재치료전후혈지적각항지표이급서장압、수축압도유소강저，차량조지간유현저성차이（P＜0.05）；관찰조적환자재치료적서장압、수축압이급혈지적각항지표도명현비대조조저（P＜0.05）。량조환자적간신공능이급혈뇨상규재치료전후적차이몰유통계학의의（P＞0.05）。관찰조중재치료시유1례출현악심현상，단시통과약관찰격산기매이급간매，몰유이상，계속진행치료；대조조중재치료시유3례출현심황증상，단시정도재내수범위지내，계속치료지후증상호전。결론채용안록지평아탁벌타정개편대고혈압합병관심병진행치료유비상호적림상료효，가이명현개선환자적혈지화혈압수평，치득재림상상진행추엄。
Objective Analysis of the use of amlodipine and atorvastatin treatment effect on hypertension complicated with coronary artery disease. Methods 98 patients with hypertension and coronary heart disease in our hospital during the period of 2010 May-2012 year in May admit ed to the patients, the patients were randomly divided into two groups, method of taking oral y amlodipine and atorvastatin calcium tablets in the observation group 50 patients were treated, 48 patients in the control group were taken oral y amlodipine and atorvastatin atorvastatin calcium treatment, then the two groups of patients in the changes of blood lipid and blood pressure were observed and compared before and after treatment. Results Two groups of patients before and after treatment in al indexes of blood lipid and diastolic blood pressure, systolic blood pressure decreased, and there is a signiifcant difference between the two groups (P<0.05 );observation group in the treatment of patients with diastolic blood pressure, systolic blood pressure and blood lipid indicators are signiifcantly lower than the control group (P<0.05). The two groups of patients with hepatic and renal function, blood and urine routine in the difference before and after treatment was not statistical y signiifcant (P>0.05). Observation group had 1 cases of nausea in the treatment, but the observation stimulated muscle enzyme and acid, liver enzymes, without exception, to continue the treatment;the control group had 3 patients appeared lfustered symptoms in treatment, but in the tolerance range, to continue treatment after symptoms improved. Conclusion Amlodipine and atorvastatin calcium tablets on hypertension and coronary heart disease treatment curative effect is very good, can signiifcantly improve the blood lipid and blood pressure levels in patients, worth in clinical promotion.