CAJ | 학술논문

　　目的探讨肌钙蛋白T和B型尿钠肽水平改变对心力衰竭患者预后影响。方法选择我院慢性心力衰竭患者共46例，作为观察组，心功能Ⅱ级、心功能Ⅲ级和心功能Ⅳ级患者分别为12例，23例和11例。同时选择同期到我院体检的健康者40例，作为对照组。检测所选对象肌钙蛋白T和B型尿钠肽水平。结果观察组肌钙蛋白T、B型尿钠肽水平高于对照组，差异有统计学意义（P＜0.05）；心功能Ⅳ级患者肌钙蛋白T和B型尿钠肽水平高于心功能Ⅲ级患者，差异有统计学意义（P＜0.05）；心功能Ⅲ级患者B型尿钠肽水平高于心功能Ⅱ级患者，差异有统计学意义（P＜0.05）。结论肌钙蛋白T和B型尿钠肽水平有助于了解慢性心力衰竭患者预后，具有重要临床意义。
　　목적탐토기개단백T화B형뇨납태수평개변대심력쇠갈환자예후영향。방법선택아원만성심력쇠갈환자공46례，작위관찰조，심공능Ⅱ급、심공능Ⅲ급화심공능Ⅳ급환자분별위12례，23례화11례。동시선택동기도아원체검적건강자40례，작위대조조。검측소선대상기개단백T화B형뇨납태수평。결과관찰조기개단백T、B형뇨납태수평고우대조조，차이유통계학의의（P＜0.05）；심공능Ⅳ급환자기개단백T화B형뇨납태수평고우심공능Ⅲ급환자，차이유통계학의의（P＜0.05）；심공능Ⅲ급환자B형뇨납태수평고우심공능Ⅱ급환자，차이유통계학의의（P＜0.05）。결론기개단백T화B형뇨납태수평유조우료해만성심력쇠갈환자예후，구유중요림상의의。
Objective To investigate the change of cardiac troponin T and B type natriuretic peptide levels on the prognosis of patients with heart failure. Methods 46 cases with chronic heart failure patients as the observation group were selected,the patients with gradeⅡof cardiac function was 12cases, the patients with gradeⅢof cardiac function was 23cases,the patients with grade IV of cardiac function was 11cases. 40 cases with physical health were selected as the control group at the same period,level.of troponin T and B type natriuretic peptide was detected. Results Level of cardiac troponin T, B type natriuretic peptide in the observation group was higher than those in control group, the difference was statistically signiifcant(P<0.05);cardiac troponin T and B type natriuretic peptide levels of the patients with heart function class IV was higher than those of the patients with cardiac function grade III, the difference was statistically signiifcant(P<0.05);cardiac troponin T and B type natriuretic peptide levels of the patients with heart function class III was higher than those of the patients with cardiac function gradeⅡ, the difference was statistically signiifcant (P<0.05).Conclusions Troponin T and B type natriuretic peptide levels contribute to the understanding of the prognosis of chronic heart failure patients, and which has important clinical signiifcance.