CAJ | 학술논문

　　目的探讨应用放射性125 I粒子组织间植入预防涎腺恶性肿瘤复发的初步疗效。方法24例涎腺恶性肿瘤经手术完整切除，术后利用放射性125 I粒子组织间植入预防复发，其中14例为腮腺，7例为下颌下腺，2例为舌下腺，1例为磨牙后区小涎腺。结果随访5～72个月，22例患者局部未复发，未发生远处转移；2例患者局部无复发，但出现区域转移和肺部转移。结论放射性125 I粒子组织内植入能有效控制涎腺恶性肿瘤术后的局部复发率，但对于高度恶性涎腺肿瘤，仍有发生局域及远处转移的可能，需要结合术后化疗。
　　목적탐토응용방사성125 I입자조직간식입예방연선악성종류복발적초보료효。방법24례연선악성종류경수술완정절제，술후이용방사성125 I입자조직간식입예방복발，기중14례위시선，7례위하합하선，2례위설하선，1례위마아후구소연선。결과수방5～72개월，22례환자국부미복발，미발생원처전이；2례환자국부무복발，단출현구역전이화폐부전이。결론방사성125 I입자조직내식입능유효공제연선악성종류술후적국부복발솔，단대우고도악성연선종류，잉유발생국역급원처전이적가능，수요결합술후화료。
Objective To investigate the recurrence rate of radioactive 125-iodine seed implant brachytherapy of the salivary malignancy that have been operated. Methods Twenty-four patients with postoperative salivary malignancy were treated by radioactive 125-iodine seed implanting. Fourteen patients were malignant parotid gland tumors. Seven were submandibular gland. Two were sublingual gland. The other one was small salivary malignancy. Results All the patients were followed up for 5-72 months. Twenty-two patients of the group were found the recurrence on operating ifeld and distant metastasis. Two patients were found regional metastasis and pulmonary metastasis. Conclusion The radioactive 125-iodine seed implant brachytherapy of postoperative salivary malignancy is very effective to control the local recurrence rate. But there are some of them have the possibility occurring regional metastasis or distant metastasis.