CAJ | 학술논문

目的总结下肢动脉硬化闭塞症(peripheral arterial occlusive disease,PAOD)需血管重建术患者无症状重度颈动脉狭窄(asymptomatic carotid stenosis,ACS)发生率、临床特点及其相关危险因素,探讨PAOD术前行颈动脉超声筛查重度ACS的临床价值.方法回顾性分析229例需血管重建术治疗的重度PAOD患者的临床资料,术前均行颈动脉超声检查筛查ACS,并将PAOD患者分为重度ACS组(ACS ≥70％)和非重度ACS组(ACS＜ 70％),对2组患者临床特点及相关危险因素进行分析.结果 229例患者中,重度ACS发生率为19.7％;重度ACS组患者年龄、血压、总胆固醇和纤维蛋白原水平明显高于非重度ACS组,差异有统计学意义(P＜0.05);PAOD症状越重的患者重度ACS的发生率越高;多因素Logistic回归分析显示高龄、高血压以及高胆固醇血症是重度ACS预测指标.结论 PAOD症状严重程度与重度ACS发生率呈正相关且高龄、高血压以及高胆固醇血症是重度ACS的独立危险因素.
목적 총결하지동맥경화폐새증(peripheral arterial occlusive disease,PAOD)수혈관중건술환자무증상중도경동맥협착(asymptomatic carotid stenosis,ACS)발생솔、림상특점급기상관위험인소,탐토PAOD술전행경동맥초성사사중도ACS적림상개치.방법 회고성분석229례수혈관중건술치료적중도PAOD환자적림상자료,술전균행경동맥초성검사사사ACS,병장PAOD환자분위중도ACS조(ACS ≥70％)화비중도ACS조(ACS＜ 70％),대2조환자림상특점급상관위험인소진행분석.결과 229례환자중,중도ACS발생솔위19.7％;중도ACS조환자년령、혈압、총담고순화섬유단백원수평명현고우비중도ACS조,차이유통계학의의(P＜0.05);PAOD증상월중적환자중도ACS적발생솔월고;다인소Logistic회귀분석현시고령、고혈압이급고담고순혈증시중도ACS예측지표.결론 PAOD증상엄중정도여중도ACS발생솔정정상관차고령、고혈압이급고담고순혈증시중도ACS적독립위험인소.
Objective To evaluate the incidence of asymptomatic carotid stenosis (ACS) in patients with peripheral arterial occlusive disease (PAOD) who was admitted for revascularization.Methods 229 PAOD patients were evaluated by carotid ultrasound preoperatively and divided into severe ACS group (ACS ≥ 70％) and non severe ACS group (ACS ＜ 70％).The clinical characteristics and associated risk factors of the two groups were analyzed.Results The incidence of severe ACS was 19.7％,age,blood pressure,total cholesterol and fibrinogen levels in severe ACS group were significantly higher than those in non-severe ACS group (P ＜ 0.05),the more severe the symptoms of PAOD are,the higher is the incidence of severe ACS.Age,hypertension and hypercholesterolemia were all predictors of severe ACS.Conclusions The severity of PAOD is positively correlated with the incidence of severe ACS.Age,hypertension and hypercholesterolemia are independent risk factors for severe ACS.