CAJ | 학술논문

目的探讨肝动脉介入栓塞化疗(TACE)联合三维适形技术指导微波消融(PMCT)治疗原发性肝癌的临床应用价值.方法选取临床诊断结合影像检查诊断为原发性肝癌的患者80例,因种种原因无法直接行手术切除而纳入本研究,将其统一编号后随机抽取分成两组,研究组40例先行TACE治疗后再利用三维适形技术指导微波消融(PMCT)治疗,对照组40例单纯行TACE治疗.比较两组患者肿瘤坏死率、复发率、平均生存期.结果研究组的肿瘤平均坏死率81.0％明显高于对照组的42％,两组一年内局部复发率分别为30.5％、44.8％.研究组的平均生存期为21.0个月,高于对照组的16.8个月.结论利用肝动脉栓塞化疗联合三维适形技术指导微波消融治疗原发性肝癌,可大大提高肿瘤组织坏死率,延长生存期,明显提高疗效.
목적 탐토간동맥개입전새화료(TACE)연합삼유괄형기술지도미파소융(PMCT)치료원발성간암적림상응용개치.방법 선취림상진단결합영상검사진단위원발성간암적환자80례,인충충원인무법직접행수술절제이납입본연구,장기통일편호후수궤추취분성량조,연구조40례선행TACE치료후재이용삼유괄형기술지도미파소융(PMCT)치료,대조조40례단순행TACE치료.비교량조환자종류배사솔、복발솔、평균생존기.결과 연구조적종류평균배사솔81.0％명현고우대조조적42％,량조일년내국부복발솔분별위30.5％、44.8％.연구조적평균생존기위21.0개월,고우대조조적16.8개월.결론 이용간동맥전새화료연합삼유괄형기술지도미파소융치료원발성간암,가대대제고종류조직배사솔,연장생존기,명현제고료효.
Objective To study the transcatheter arterial embolization and chemotherapy (TACE) combined with three-dimensional conformal techniques guided microwave ablation (PMCT) in the treatment of primary liver cancer clinical application value.Methods 80 cases diagnosed as primary liver cancer by clinical diagnosis with imaging examination were selected,due to a variety of reason they couldn't receive direct operation and had to be included in this cohort study,after the number uniform they were randomly divided into two groups (the average age of lesion size and grade of liver function of 2 groups showed no significant difference),40 cases used three-dimensional conformal techniques guided microwave ablation treatment after first TACE treatment (study group),40 cases received simple TACE treatment (control group).The tumor necrosis rate,recurrence rate and the mean survival period of the 2 groups were compared.Results The average tumor necrosis of study group was significantly higher than that of control (81.0％ vs 42％,P＜0.05).The local recurrence rate (one year) of two groups were 30.5％ and 44.8％ respectively,with statistical significant difference (P＜0.05).The average survival time of study group was 21 months,higher than that of control group (16.8 months),with significant differences (P＜0.05).Conclusion Use of hepatic artery embolism chemotherapy combined with three-dimensional conformal techniques guided microwave ablation therapy of hepatocellular carcinoma,can greatly improve the tumor tissue necrosis rate,prolong the survival time and improve therapeutic effect.