CAJ | 학술논문

目的：探讨初发急性脑梗死发病与时间变化的关系，以采取相应的预防措施应对气候变化。方法回顾性分析1198例初发急性脑梗死患者的资料，结合患者一般资料分析初发急性脑梗死发病的年、季节、月及周变化规律。结果从2009-2013年，初发急性脑梗死发病逐年增加，且具有季节变化规律，冬季为发病高峰（30.33±9.63）例次/月，春季为低谷（21.83±5.36）例次/月。初发急性脑梗死季节规律与既往有无吸烟史、饮酒史、高血压、冠心病、糖尿病等高危因素无关。脑梗死合并肺炎的发病有季节性差异（P<0.01），冬季发病率（19.8%）较其他季节高（春16.4%，夏12.7%，秋10.8%）。初发急性脑梗死发病同时具有月变化规律（P=0.010），1～2月为发病高峰（33.25±9.62）例次/月，3～4月为发病低谷（20.75±4.89）例次/月。初发急性脑梗死发病具有周变化规律（P=0.043），以星期一为高峰（17.86%），星期五最低（13.36%）。结论研究时段内初发急性脑梗死发病呈逐年上升趋势，且具有季节、月及周变化规律，为制定相应防治措施提供了依据。
목적：탐토초발급성뇌경사발병여시간변화적관계，이채취상응적예방조시응대기후변화。방법회고성분석1198례초발급성뇌경사환자적자료，결합환자일반자료분석초발급성뇌경사발병적년、계절、월급주변화규률。결과종2009-2013년，초발급성뇌경사발병축년증가，차구유계절변화규률，동계위발병고봉（30.33±9.63）례차/월，춘계위저곡（21.83±5.36）례차/월。초발급성뇌경사계절규률여기왕유무흡연사、음주사、고혈압、관심병、당뇨병등고위인소무관。뇌경사합병폐염적발병유계절성차이（P<0.01），동계발병솔（19.8%）교기타계절고（춘16.4%，하12.7%，추10.8%）。초발급성뇌경사발병동시구유월변화규률（P=0.010），1～2월위발병고봉（33.25±9.62）례차/월，3～4월위발병저곡（20.75±4.89）례차/월。초발급성뇌경사발병구유주변화규률（P=0.043），이성기일위고봉（17.86%），성기오최저（13.36%）。결론연구시단내초발급성뇌경사발병정축년상승추세，차구유계절、월급주변화규률，위제정상응방치조시제공료의거。
Objective Investigating the relationship between the incidence of Primary Acute Cerebral Infarction (PACI) and seasonal variation to employ measures to prevent PACI with climate change. Methods A retrospective analysis of patients diagnosed with PACI between 2009 and 2013 in the department of Neurology of Second hospital of Tian Jin Medi-cal University (n=1 198 patients) was carried out. Combined with the general clinical data, we analyzed seasonal, monthly and weekly variation among PACI incidents. Results The incidence of PACI increases over years between 2009 to 2013 (P < 0.01). Significant difference of incidents of PACI was observed between each season (P=0.047). Incidence of PACI peaked in winter(30.33 ± 9.63/month), while bottomed in spring(21.83 ± 5.36/month). Significant difference of incidents of PACI was also observed between each months(P=0.010). The monthly incidence was highest in January and February (33.25 ± 9.62/month)and lowest in March and April(20.75 ± 4.89/month). The seasonal variation was only found in the pa-tients who are complicated with pulmonary infection (P<0.01) regardless of the presence or absence of other risk factors, such as smoking, drinking ,hypertension, coronary heart disease, and diabetes mellitus. The weekly variation of PACI was on-ly significant in patients younger than 65 years old(P=0.043). The peak incidence among a week was Monday(17.86%),and incidence bottomed on Friday (13.36%). Conclusion Our study revealed that the incidence of PACI increase over year be-tween 2009 to 2013 and it shew a characteristic variation with respect to season, month and week. Based on these results, we can formulate prevention measures accordingly.