CAJ | 학술논문

目的：探讨巨脑回畸形与脑室周围白质软化症(PVL)导致的脑瘫临床表现、预后等方面的区别与联系。方法回顾性研究巨脑回所致脑瘫15例和PVL所致脑瘫35例，比较种不同原因所致脑瘫在确诊年龄、分型、并发症、粗大运动功能分级(GMF-CS)等方面的不同。结果巨脑回畸形组所致脑瘫患儿确诊年龄要显著早于PVL组(P<0.001)，GMFCS分级低于PVL组(P<0.05)，癫痫发生率高于PVL组(P<0.05)，智力显著低于PVL组(P<0.001)。结论巨脑回畸形所致脑瘫整体发育比PVL发育要差，其预后也相对较差。
목적：탐토거뇌회기형여뇌실주위백질연화증(PVL)도치적뇌탄림상표현、예후등방면적구별여련계。방법회고성연구거뇌회소치뇌탄15례화PVL소치뇌탄35례，비교충불동원인소치뇌탄재학진년령、분형、병발증、조대운동공능분급(GMF-CS)등방면적불동。결과거뇌회기형조소치뇌탄환인학진년령요현저조우PVL조(P<0.001)，GMFCS분급저우PVL조(P<0.05)，전간발생솔고우PVL조(P<0.05)，지력현저저우PVL조(P<0.001)。결론거뇌회기형소치뇌탄정체발육비PVL발육요차，기예후야상대교차。
Objective To compare the features of cerebral palsy with pachygyria or periventricular leukomalacia (PVL). Methods 15 children with pachygyria and 35 children with PVL were included. Their diagnosed age, clinical subtype, complications, Gross Motor Func-tion Classification System (GMFCS) were compared. Results The diagnosed age was significantly younger (P<0.001), the GMFCS was lower (P<0.05), the incidence rate of epilepsy was higher (P<0.05), and the intelligence was significantly lower (P<0.001) in the pachygyria group than in the PVL group. Conclusion Cerebral palsy children with pachygyria develope worse than that with PVL, as well as their prog-nosis.