CAJ | 학술논문

目的：探讨T1灌注加权成像对颈部转移性淋巴结的诊断价值及年龄因素是否影响灌注结果。方法对18例颈部淋巴结转移患者(病例组)和30例健康人(正常组)行T1灌注加权成像，对半定量参数流入速率、流出速率、最大相对增强率和峰值时间以时间-信号曲线进行分析。以40岁为界分析年龄对灌注的影响。结果流入速率在2组之间有统计学差异(P<0.05)，转移性淋巴结(n=23)流入速率高于正常组淋巴结(n=49)，最大相对增强率、流出速率以及峰值时间二者无差异(P>0.05)。正常淋巴结与转移性淋巴结的时间-信号曲线类型均以Ⅱ型为主。最大相对增强率、流入速率与年龄呈负相关关系。40岁以下组的最大相对增强率和流入速率高于40岁以上组。结论流入速率有助于鉴别正常淋巴结与转移性淋巴结，进行灌注分析时需要考虑年龄因素的影响。
목적：탐토T1관주가권성상대경부전이성림파결적진단개치급년령인소시부영향관주결과。방법대18례경부림파결전이환자(병례조)화30례건강인(정상조)행T1관주가권성상，대반정량삼수류입속솔、류출속솔、최대상대증강솔화봉치시간이시간-신호곡선진행분석。이40세위계분석년령대관주적영향。결과류입속솔재2조지간유통계학차이(P<0.05)，전이성림파결(n=23)류입속솔고우정상조림파결(n=49)，최대상대증강솔、류출속솔이급봉치시간이자무차이(P>0.05)。정상림파결여전이성림파결적시간-신호곡선류형균이Ⅱ형위주。최대상대증강솔、류입속솔여년령정부상관관계。40세이하조적최대상대증강솔화류입속솔고우40세이상조。결론류입속솔유조우감별정상림파결여전이성림파결，진행관주분석시수요고필년령인소적영향。
Objective To investigate the diagnostic value of cervical metastatic lymph nodes by T1 perfusion-weighted imaging and analyse the effect of age on perfusion.Methods 18 cases of cervical lymph node metastasis (case group)and 30 healthy people (control group)were performed T1 perfusion-weighted imaging.The semi-quantitative parameters (including in maximum relative enhancement ratio,wash in rate,wash out rate and peak time)and time-intensity curve (TIC)were compared between case group and control group.Moreover,the effect of age on perfusion was investigated by the age of 40 years old.Results The inflow rate was statistically significant difference between the two groups (P<0.05)and that of 23 cases of metastatic lymph nodes was higher than 49 normal lymph nodes.However,the maximum relative enhancement ratio,outflow rate and peak time weren’t statistically signif-icant difference(P>0.05).The time-intensity curve in metastatic lymph nodes and normal lymph nodes were common in typeⅡ. The maximum relative enhancement ratio and wash in rate negatively correlated with the age and the maximum relative enhancement ratio and wash in rate below the age of 40 years old were higher than above the age 40.Conclusion The wash in rate is helpful to dif-ferentiate metastatic lymph nodes and normal lymph nodes.The effect of age on perfusion is considered.