CAJ | 학술논문

目的：了解在药学干预前后我院住院患者抗菌药物使用强度(AUD)的变化。方法：以限定日剂量(DDD)为单位，计算抗菌药物使用强度(AUD)并进行分析。结果：药学干预前、后我院住院患者抗菌药物的AUD分别为61.90DDD/100人/天、47.54 DDD/100人/天；药学干预前，我院二代头孢菌素、硝咪唑类、三代头孢菌素的AUD列前3位，干预后二代头孢菌素、头霉素类、硝基咪唑类的AUD列前3位；我院AUD排列前10位的抗菌药物为奥硝唑注射液、头孢呋辛钠、头孢唑肟钠、头孢美唑钠、头孢西丁钠、左氧氟沙星注射液等；药学干预后大部分临床科室的抗菌药物使用强度均下降。结论：药学干预前我院抗菌药物的使用存在用药剂量过大、用药疗程过长、选药不当等问题，应进一步加强抗菌药物应用的监督管理。
목적：료해재약학간예전후아원주원환자항균약물사용강도(AUD)적변화。방법：이한정일제량(DDD)위단위，계산항균약물사용강도(AUD)병진행분석。결과：약학간예전、후아원주원환자항균약물적AUD분별위61.90DDD/100인/천、47.54 DDD/100인/천；약학간예전，아원이대두포균소、초미서류、삼대두포균소적AUD렬전3위，간예후이대두포균소、두매소류、초기미서류적AUD렬전3위；아원AUD배렬전10위적항균약물위오초서주사액、두포부신납、두포서우납、두포미서납、두포서정납、좌양불사성주사액등；약학간예후대부분림상과실적항균약물사용강도균하강。결론：약학간예전아원항균약물적사용존재용약제량과대、용약료정과장、선약불당등문제，응진일보가강항균약물응용적감독관리。
Objective:The study was conducted in order to have a clear knowledge of the AUD of antibiotics taken by patients in Miyun Hospital before and after pharmaceutical intervention. Methods: Calculate and analyze the AUD of antibiotics taken by patients in Miyun Hospital by the unit of DDD. Results: Before pharmaceutical intervention, second-generation cephalosporins, nitrate imidazole, and third-generation cephalosporins ranked the first 3 in AUD, the antibiotic AUD was 61.90 DDD/100 person/day;While after pharmaceutical intervention, second-generation cephalosporins, and cephamycins, nitrate imidazole ranked the first 3, AUD has dropped to 47.54 DDD/100 person/day. The antibiotic AUD has obviously decreased in most departments in our hospital due to pharmaceutical intervention. Conclusion:Before pharmaceutical intervention, there were some problems on the application of antibiotics in our hospital, including high doses, long course of treatment, and improper choice of antibiotics. Supervision of application of antibiotics should be further emphasized.