中国药物评价
中國藥物評價
중국약물평개
Chinese Journal of Drug Evaluation
2014年
3期
152-158
,共7页
徐丹妮%马骏捷%马爱霞
徐丹妮%馬駿捷%馬愛霞
서단니%마준첩%마애하
纳洛酮%GM1%颅脑损伤%间接Meta分析
納洛酮%GM1%顱腦損傷%間接Meta分析
납락동%GM1%로뇌손상%간접Meta분석
Naloxone%GM1%Head Injury%Indirect Meta-analysis
目的：系统评价纳洛酮和单唾液酸四己糖神经节苷脂（GM1）治疗颅脑损伤的疗效。方法：以间接Meta分析的方法对已有研究进行合并，系统评价两种药物治疗颅脑损伤的GOS恢复良好率。结果：纳洛酮和GM1的GOS恢复良好率分别为69.15％和55.61％。结论：在治疗颅脑损伤的GOS恢复良好率方面，纳洛酮明显优于GM1。
目的：繫統評價納洛酮和單唾液痠四己糖神經節苷脂（GM1）治療顱腦損傷的療效。方法：以間接Meta分析的方法對已有研究進行閤併，繫統評價兩種藥物治療顱腦損傷的GOS恢複良好率。結果：納洛酮和GM1的GOS恢複良好率分彆為69.15％和55.61％。結論：在治療顱腦損傷的GOS恢複良好率方麵，納洛酮明顯優于GM1。
목적：계통평개납락동화단타액산사기당신경절감지（GM1）치료로뇌손상적료효。방법：이간접Meta분석적방법대이유연구진행합병，계통평개량충약물치료로뇌손상적GOS회복량호솔。결과：납락동화GM1적GOS회복량호솔분별위69.15％화55.61％。결론：재치료로뇌손상적GOS회복량호솔방면，납락동명현우우GM1。
Objective: To systematically evaluate the efficacy of curative effects of treating head injury between naloxone and GM1.Methods:GOS good recovery rate was taken as effectiveness indicator.An indirect Meta-analysis was developed.Results:The GOS good recovery rates are 69.15%and 55.61%for naloxone and GM1 respectively.Conclusion:The research showed that GOS good recov-ery rate in naloxone arm is better than that in GM 1 arm.
