中国药物评价
中國藥物評價
중국약물평개
Chinese Journal of Drug Evaluation
2014年
3期
138-141,145
,共5页
益肾壮阳膏%勃起功能障碍%临床疗效%分析
益腎壯暘膏%勃起功能障礙%臨床療效%分析
익신장양고%발기공능장애%림상료효%분석
Yi Shen Zhuang Yang Cream%Erectile dysfunction%Clinical effect%Analysis
目的:对益肾壮阳膏药效学进行研究和总结,以期为中药新药研发提供参考。方法:选用多种动物模型,对雄性去势大鼠的阴茎勃起功能、雄性大鼠交配能力、实验性肾阳虚动物(大鼠、小鼠)的性腺器官大小和免疫功能进行实验研究。结果:益肾壮阳膏对去势引起的大鼠阴茎勃起功能障碍有明显的恢复作用、对正常大鼠的交配能力有一定的增强作用、对阳虚大鼠的性腺器官指数降低有一定的恢复作用,对阳虚小鼠的免疫功能有明显的增强作用,对阳虚小鼠的体重有一定的恢复作用。结论:益肾壮阳膏有一定的壮阳、免疫增强和增加阳虚动物体重的作用。
目的:對益腎壯暘膏藥效學進行研究和總結,以期為中藥新藥研髮提供參攷。方法:選用多種動物模型,對雄性去勢大鼠的陰莖勃起功能、雄性大鼠交配能力、實驗性腎暘虛動物(大鼠、小鼠)的性腺器官大小和免疫功能進行實驗研究。結果:益腎壯暘膏對去勢引起的大鼠陰莖勃起功能障礙有明顯的恢複作用、對正常大鼠的交配能力有一定的增彊作用、對暘虛大鼠的性腺器官指數降低有一定的恢複作用,對暘虛小鼠的免疫功能有明顯的增彊作用,對暘虛小鼠的體重有一定的恢複作用。結論:益腎壯暘膏有一定的壯暘、免疫增彊和增加暘虛動物體重的作用。
목적:대익신장양고약효학진행연구화총결,이기위중약신약연발제공삼고。방법:선용다충동물모형,대웅성거세대서적음경발기공능、웅성대서교배능력、실험성신양허동물(대서、소서)적성선기관대소화면역공능진행실험연구。결과:익신장양고대거세인기적대서음경발기공능장애유명현적회복작용、대정상대서적교배능력유일정적증강작용、대양허대서적성선기관지수강저유일정적회복작용,대양허소서적면역공능유명현적증강작용,대양허소서적체중유일정적회복작용。결론:익신장양고유일정적장양、면역증강화증가양허동물체중적작용。
Objective:To study and summarize the pharmacodynamic of Yi Shen Zhuang Yang cream , and to promote the innovative re-search of traditional Chinese medicine.Methods:Some animal models were selected in this article , experimental research were done on the erectile function of castrated rat , mating ability of male rat , genital organ size of experimental animal ( small and big rat ) with deficient kid-ney and their immunity.Results: The results showed that Yi Shen Zhuang Yang Cream has helped with recovery of erectile dysfunction ( ED) of castrated rat , enhanced the mating ability of normal rat , in some way restored the lowered index of genital organs of the rat with deficient kidney , enhanced the immunity of small rat with deficient Yang and increased the weight of small rat with deficient Yang .Conclusion:It is concluded that Yi Shen Zhuang Yang Cream could enhance the Yang , immunity and weight of animals with Yang deficiency.