CAJ | 학술논문

降钙素原(procalcitonin,PCT)是近年来发现的感染性疾病的标记物,研究认为在细菌所致炎症或感染性疾病中特异性升高,尤其在血流感染、细菌性与非细菌性的鉴别、抗生素的合理使用及预测疾病预后方面有重要作用,是一种有很高应用价值的诊断指标,而PCT在新生儿感染疾病诊断中并没有体现出明显的优势.本文对PCT的构成、体内来源、代谢、实验室检测方法及在新生儿感染中的应用进行综述,以更深刻了解PCT在新生儿感染性疾病诊断中的价值.
강개소원(procalcitonin,PCT)시근년래발현적감염성질병적표기물,연구인위재세균소치염증혹감염성질병중특이성승고,우기재혈류감염、세균성여비세균성적감별、항생소적합리사용급예측질병예후방면유중요작용,시일충유흔고응용개치적진단지표,이PCT재신생인감염질병진단중병몰유체현출명현적우세.본문대PCT적구성、체내래원、대사、실험실검측방법급재신생인감염중적응용진행종술,이경심각료해PCT재신생인감염성질병진단중적개치.
Procalcitonin (PCT) has been recognized a marker of infectious diseases for the past few years.The value of PCT is specific elevation in infectious diseases or inflammation caused by bacterial and it has an important role in the identification of bloodstream infections,bacterial and non-bacterial,rational usage of antibiotics and prediction disease prognosis.PCT is a high value diagnostic indicators.However,the PCT do not reflect a clear advantage in the diagnosis of neonatal infection.In this paper,the composition of the PCT,the source in the body of PCT,the metabolism of PCT,laboratory testing methods of PCT and its applications in neonatal infection were reviewed in order to gain a deeper understanding of the value of PCT in the neonatal diagnosis of infectious diseases.