CAJ | 학술논문

妊娠妇女银屑病的治疗与普通人群银屑病的治疗不同,不仅要考虑治疗方法的有效性,还应尽量避免对孕妇及胎儿产生的不良影响.目前,关于妊娠妇女银屑病的治疗主要有局部疗法、光疗法和系统疗法,尚无统一规范.首选局部疗法,外用糖皮质激素类药物被认为是一线疗法;光疗法中最常用的是中波紫外线;系统用药如维A酸类药物、糖皮质激素、免疫抑制剂及生物制剂,但可能对妊娠妇女自身产生不良影响,也可能导致胎儿宫内发育迟缓、畸胎、低出生体重儿等不良反应,因此,妊娠妇女的银屑病应慎用系统疗法.
임신부녀은설병적치료여보통인군은설병적치료불동,불부요고필치료방법적유효성,환응진량피면대잉부급태인산생적불량영향.목전,관우임신부녀은설병적치료주요유국부요법、광요법화계통요법,상무통일규범.수선국부요법,외용당피질격소류약물피인위시일선요법;광요법중최상용적시중파자외선;계통용약여유A산류약물、당피질격소、면역억제제급생물제제,단가능대임신부녀자신산생불량영향,야가능도치태인궁내발육지완、기태、저출생체중인등불량반응,인차,임신부녀적은설병응신용계통요법.
The treatment of psoriasis in pregnancy is different from that of conventional psoriasis.Both efficacy and negative effects on patients and their fetuses should be taken into considerations for the treatment of pregnant women with psoriasis,which mainly includes topical therapy,phototherapy and systemic therapy at present.Topical therapy is the preferred choice,and topical corticosteroids are considered as the first-line treatment.Narrow band-ultraviolet B (NB-UVB) is the most commonly used light source for the phototherapy of psoriasis in pregnancy.Systemic treatments such as retinoids,corticosteroids,immunosuppressants and biologics,not only have a negative effect on pregnant women themselves,but also are associated with intrauterine growth retardation,teratogenesis and low birth weight newnates.Hence,systemic treatments should be used with caution in pregnant women with psoriasis.