西南国防医药
西南國防醫藥
서남국방의약
MEDICAL JOURNAL OF NATIONAL DEFENDING FORCES IN SOUTHWEST CHINA
2014年
6期
581-583
,共3页
脑室%引流%脑室炎%危险因素
腦室%引流%腦室炎%危險因素
뇌실%인류%뇌실염%위험인소
ventricle%drainage%ventriculitis%risk factors
目的：探讨脑室外引流发生脑室炎的相关危险因素。方法回顾性分析2007年1月~2012年12月于泸州市人民医院接受脑室外引流的300例患者的临床资料，根据脑室感染情况分为脑室炎组和对照组。对可能的危险因素进行单因素和多因素Logistic回归分析。结果单因素分析发现，脑室炎症的发生与手术时间（﹥4 h）、引流天数（≥7 d）、手术次数（≥2次）、切口脑脊液漏、尿激酶脑室灌注、原发疾病等因素有相关性（P﹤0.05或P﹤0.01），与性别、年龄等因素无相关性；多因素Logistic回归发现，手术时间、引流天数、手术次数、切口脑脊液漏、尿激酶脑室灌注、原发疾病皆是脑室外引流患者脑室炎症的独立危险因素。结论脑室外引流发生脑室炎是多因素共同作用的结果，手术时间、引流天数、手术次数、切口脑脊液漏、尿激酶脑室灌注、原发疾病是术后脑室炎的独立危险因素。及早针对危险因素采取有效的预防措施，有助于降低脑室炎症的发生。
目的：探討腦室外引流髮生腦室炎的相關危險因素。方法迴顧性分析2007年1月~2012年12月于瀘州市人民醫院接受腦室外引流的300例患者的臨床資料，根據腦室感染情況分為腦室炎組和對照組。對可能的危險因素進行單因素和多因素Logistic迴歸分析。結果單因素分析髮現，腦室炎癥的髮生與手術時間（﹥4 h）、引流天數（≥7 d）、手術次數（≥2次）、切口腦脊液漏、尿激酶腦室灌註、原髮疾病等因素有相關性（P﹤0.05或P﹤0.01），與性彆、年齡等因素無相關性；多因素Logistic迴歸髮現，手術時間、引流天數、手術次數、切口腦脊液漏、尿激酶腦室灌註、原髮疾病皆是腦室外引流患者腦室炎癥的獨立危險因素。結論腦室外引流髮生腦室炎是多因素共同作用的結果，手術時間、引流天數、手術次數、切口腦脊液漏、尿激酶腦室灌註、原髮疾病是術後腦室炎的獨立危險因素。及早針對危險因素採取有效的預防措施，有助于降低腦室炎癥的髮生。
목적：탐토뇌실외인류발생뇌실염적상관위험인소。방법회고성분석2007년1월~2012년12월우로주시인민의원접수뇌실외인류적300례환자적림상자료，근거뇌실감염정황분위뇌실염조화대조조。대가능적위험인소진행단인소화다인소Logistic회귀분석。결과단인소분석발현，뇌실염증적발생여수술시간（﹥4 h）、인류천수（≥7 d）、수술차수（≥2차）、절구뇌척액루、뇨격매뇌실관주、원발질병등인소유상관성（P﹤0.05혹P﹤0.01），여성별、년령등인소무상관성；다인소Logistic회귀발현，수술시간、인류천수、수술차수、절구뇌척액루、뇨격매뇌실관주、원발질병개시뇌실외인류환자뇌실염증적독립위험인소。결론뇌실외인류발생뇌실염시다인소공동작용적결과，수술시간、인류천수、수술차수、절구뇌척액루、뇨격매뇌실관주、원발질병시술후뇌실염적독립위험인소。급조침대위험인소채취유효적예방조시，유조우강저뇌실염증적발생。
Objective To explore the risk factors in the occurrence of postoperative ventriculitis in patients with external ventricular drainage. Methods A retrospective analysis was made to the clinical data of 300 patients of external ventricular drainage made in the People′s Hospital of Luzhou City during the time from January 2007 to December 2012;based on the degree of ventricular infection,the patients were divided into 2 groups:ventriculitis group and control group. Univariate and multiple logistic regression analysis was used to determine the possible risk factors associated with ventriculitis. Results Univariate logistic regression analysis showed that the occurrence of ventriculitis was mainly correlated to operation time length( ﹥4 h),days of external ventricular drainage (≥7 days),times of operations(≥2),cerebrospinal fluid leakage,intraventricular perfusion of urokinase,primary diseases( P﹤0. 05 or P﹤0. 01),while it was not correlated to sex and age;multiple logistic regression analysis found that operation time length,days of external ventricular drainage,operations times,cerebrospinal fluid leakage,intraventricular perfusion of urokinase,primary diseases were the independent risk factors for ventriculitis in patients of external ventricular drainage. Conclusions Ventriculitis after external ventricular drainage occurs due to the interaction of multiple factors,and operation time length,days of external ventricular drainage, operations times,cerebrospinal fluid leakage,intraventricular perfusion of urokinase,primary diseases are the independent risk factors;early preventive measures against ventriculitis can reduce the occurrence.
