陕西医学杂志
陝西醫學雜誌
협서의학잡지
SHAANXI MEDICAL JOURNAL
2014年
6期
648-649,666
,共3页
田林涛%王宗超%梁漫%王新梅%田亚宁%王越月%李宏%何春玲%董昌虎
田林濤%王宗超%樑漫%王新梅%田亞寧%王越月%李宏%何春玲%董昌虎
전림도%왕종초%량만%왕신매%전아저%왕월월%리굉%하춘령%동창호
原发性骨髓纤维化%血小板增多%抗原,CD34%骨髓细胞
原髮性骨髓纖維化%血小闆增多%抗原,CD34%骨髓細胞
원발성골수섬유화%혈소판증다%항원,CD34%골수세포
Primary myelofibrosis%Thrombocytosis%Antigens,CD34%Bone marrow cells
目的：探讨CD34＋细胞在原发性骨髓纤维化症及原发性血小板增多症骨髓组织中的表达及临床意义。方法：应用免疫组织化学染色法，检测原发性骨髓纤维化症和原发性血小板增多症实验组及对照组骨髓组织中CD34＋细胞表达情况。结果：CD34＋细胞在实验组骨髓组织中表达高于对照组，差异有统计学意义（ P＜0．05）；CD34＋细胞在原发性骨髓纤维化症及原发性血小板增多症骨髓组织中表达的差异无统计学意义（ P＞0．05）。结论：CD34＋细胞在原发性骨髓纤维化症和原发性血小板增多症的发生中有一定关系，CD34＋细胞与两者之间的转化无必然联系。
目的：探討CD34＋細胞在原髮性骨髓纖維化癥及原髮性血小闆增多癥骨髓組織中的錶達及臨床意義。方法：應用免疫組織化學染色法，檢測原髮性骨髓纖維化癥和原髮性血小闆增多癥實驗組及對照組骨髓組織中CD34＋細胞錶達情況。結果：CD34＋細胞在實驗組骨髓組織中錶達高于對照組，差異有統計學意義（ P＜0．05）；CD34＋細胞在原髮性骨髓纖維化癥及原髮性血小闆增多癥骨髓組織中錶達的差異無統計學意義（ P＞0．05）。結論：CD34＋細胞在原髮性骨髓纖維化癥和原髮性血小闆增多癥的髮生中有一定關繫，CD34＋細胞與兩者之間的轉化無必然聯繫。
목적：탐토CD34＋세포재원발성골수섬유화증급원발성혈소판증다증골수조직중적표체급림상의의。방법：응용면역조직화학염색법，검측원발성골수섬유화증화원발성혈소판증다증실험조급대조조골수조직중CD34＋세포표체정황。결과：CD34＋세포재실험조골수조직중표체고우대조조，차이유통계학의의（ P＜0．05）；CD34＋세포재원발성골수섬유화증급원발성혈소판증다증골수조직중표체적차이무통계학의의（ P＞0．05）。결론：CD34＋세포재원발성골수섬유화증화원발성혈소판증다증적발생중유일정관계，CD34＋세포여량자지간적전화무필연련계。
Objective:To investigate the expression and clinical significance of CD34+ in PMF and ET . Methods :Using immunohistochemical staining to test the expression and clinical significance of CD34 in PMF and ET .Results :The CD34+ cells were highly expressed in PMF and ET than contrast ,the difference was statistically significant(P<0 .05);The CD34+ cells were expressed in PMF and ET’s bone marrow tissue ,there was no statisti-cally significant difference (P>0 .05) .Conclusion:The CD34+ cells may be not associated with MPN occurrence , development relationship ,The transformation between the not necessarily linked .
