CAJ | 학술논문

目的：了解南京地区孕晚期妇女生殖道中B族链球菌（GBS）的带菌情况。方法取本地区9073例妊娠34～37周孕妇生殖道分泌物，选取500名孕中期（20周～24周）的健康孕妇为对照组，采用荧光定量聚合酶链反应（PCR）检测 GBS，并对检测结果进行分析。结果南京地区孕晚期妇女生殖道 GBS 总带菌率为4．17％，孕中期妇女总带菌率为5．20％，两组之间差异无统计学意义（P＞0．05）。孕晚期中30～34岁组妊娠妇女带菌率最高（4．77％），与≤24岁组和≥40岁组比较，差异有统计学意义（P＜0．05），但与其他各年龄组比较差异均无统计学意义（P＞0．05）。结论南京地区晚孕期妇女GBS带菌率尚在健康人群带菌率的范围内，但也应加强检测；孕周对孕妇GBS带菌率的影响不大。
목적：료해남경지구잉만기부녀생식도중B족련구균（GBS）적대균정황。방법취본지구9073례임신34～37주잉부생식도분비물，선취500명잉중기（20주～24주）적건강잉부위대조조，채용형광정량취합매련반응（PCR）검측 GBS，병대검측결과진행분석。결과남경지구잉만기부녀생식도 GBS 총대균솔위4．17％，잉중기부녀총대균솔위5．20％，량조지간차이무통계학의의（P＞0．05）。잉만기중30～34세조임신부녀대균솔최고（4．77％），여≤24세조화≥40세조비교，차이유통계학의의（P＜0．05），단여기타각년령조비교차이균무통계학의의（P＞0．05）。결론남경지구만잉기부녀GBS대균솔상재건강인군대균솔적범위내，단야응가강검측；잉주대잉부GBS대균솔적영향불대。
Objective To evaluate the colonization of group B Streptococcus(GBS)in late pregnancy in Nanjing area.Methods The vaginal samples from 9 073 women in late pregnancy(34-37 weeks)were collected.A total of 500 cases of second trimester(20-24 weeks)of healthy pregnant women were chosen as control group.The colonization of GBS was detected by fluorescence quantitation polymerase chain reaction (PCR ). The results were analyzed comparatively.Results The results showed that the GBS carrier rate in late pregnancy was 4.1 7%,the carrier rate in second trimester pregnant women was 5 .20%,and there was no statistical significance between the 2 groups (P >0.05).The carrier rate of 30-34 years old group was the highest (4.77%),compared with≤24 years old group and≥40 years old group respectively,and the difference was statistically significant (P<0.05),but the difference with the other age groups had no statistical significance (P>0.05).Conclusions The carrier rate of GBS in late pregnancy is within the range of carrier rate of healthy population in Nanjing area.Gestational weeks have little effect on the pregnant women with GBS carrier rate.