中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
34期
1-3
,共3页
高血压%颈动脉疾病
高血壓%頸動脈疾病
고혈압%경동맥질병
Hypertension%Carotid artery diseases
目的 通过对老年原发性高血压患者血压变异性(BPV)及其与颈动脉内膜-中层厚度(IMT)的观察研究,分析老年原发性高血压患者BPV的特点及其与动脉粥样硬化的关系.方法 109例老年原发性高血压患者,均进行24 h动态血压监测(ABPM),记录24h平均收缩压(24h SBP)、24h平均舒张压(24h DBP)及其标准差;日间平均收缩压(dSBP)、日间平均舒张压(dDBP)及其标准差;夜间平均收缩压(nSBP)、夜间平均舒张压(nDBP)及其标准差.并计算各自的变异系数(CV).所有患者均进行颈动脉超声检查,测量颈动脉IMT.109例患者按颈动脉IMT结果分为非颈动脉硬化组(IMT＜ 1.0 mm,49例)和颈动脉硬化组(IMT≥1.0 mm,60例).结果 颈动脉硬化组dSBP以及24 h平均收缩压变异系数、24h平均舒张压变异系数、日间平均收缩压变异系数、夜间平均收缩压变异系数均明显高于非颈动脉硬化组[(132.3±12.1) mm Hg(1 mm Hg=0.133 kPa)比(122.7±10.8) mm Hg、0.118±0.011比0.107±0.023、0.142±0.058比0.116±0.028、0.129±0.039比0.105±0.017、0.119±0.060比0.109±0.037],差异有统计学意义(P＜ 0.01或＜0.05).两组24 hSBP、24 h DBP、dDBP、nSBP、nDBP、日间平均舒张压变异系数、夜间平均舒张压变异系数比较差异无统计学意义(P＞0.05).结论 颈动脉硬化的老年原发性高血压患者BPV明显高于非颈动脉硬化的老年原发性高血压患者,BPV与颈动脉IMT有一定的相关性.
目的 通過對老年原髮性高血壓患者血壓變異性(BPV)及其與頸動脈內膜-中層厚度(IMT)的觀察研究,分析老年原髮性高血壓患者BPV的特點及其與動脈粥樣硬化的關繫.方法 109例老年原髮性高血壓患者,均進行24 h動態血壓鑑測(ABPM),記錄24h平均收縮壓(24h SBP)、24h平均舒張壓(24h DBP)及其標準差;日間平均收縮壓(dSBP)、日間平均舒張壓(dDBP)及其標準差;夜間平均收縮壓(nSBP)、夜間平均舒張壓(nDBP)及其標準差.併計算各自的變異繫數(CV).所有患者均進行頸動脈超聲檢查,測量頸動脈IMT.109例患者按頸動脈IMT結果分為非頸動脈硬化組(IMT＜ 1.0 mm,49例)和頸動脈硬化組(IMT≥1.0 mm,60例).結果 頸動脈硬化組dSBP以及24 h平均收縮壓變異繫數、24h平均舒張壓變異繫數、日間平均收縮壓變異繫數、夜間平均收縮壓變異繫數均明顯高于非頸動脈硬化組[(132.3±12.1) mm Hg(1 mm Hg=0.133 kPa)比(122.7±10.8) mm Hg、0.118±0.011比0.107±0.023、0.142±0.058比0.116±0.028、0.129±0.039比0.105±0.017、0.119±0.060比0.109±0.037],差異有統計學意義(P＜ 0.01或＜0.05).兩組24 hSBP、24 h DBP、dDBP、nSBP、nDBP、日間平均舒張壓變異繫數、夜間平均舒張壓變異繫數比較差異無統計學意義(P＞0.05).結論 頸動脈硬化的老年原髮性高血壓患者BPV明顯高于非頸動脈硬化的老年原髮性高血壓患者,BPV與頸動脈IMT有一定的相關性.
목적 통과대노년원발성고혈압환자혈압변이성(BPV)급기여경동맥내막-중층후도(IMT)적관찰연구,분석노년원발성고혈압환자BPV적특점급기여동맥죽양경화적관계.방법 109례노년원발성고혈압환자,균진행24 h동태혈압감측(ABPM),기록24h평균수축압(24h SBP)、24h평균서장압(24h DBP)급기표준차;일간평균수축압(dSBP)、일간평균서장압(dDBP)급기표준차;야간평균수축압(nSBP)、야간평균서장압(nDBP)급기표준차.병계산각자적변이계수(CV).소유환자균진행경동맥초성검사,측량경동맥IMT.109례환자안경동맥IMT결과분위비경동맥경화조(IMT＜ 1.0 mm,49례)화경동맥경화조(IMT≥1.0 mm,60례).결과 경동맥경화조dSBP이급24 h평균수축압변이계수、24h평균서장압변이계수、일간평균수축압변이계수、야간평균수축압변이계수균명현고우비경동맥경화조[(132.3±12.1) mm Hg(1 mm Hg=0.133 kPa)비(122.7±10.8) mm Hg、0.118±0.011비0.107±0.023、0.142±0.058비0.116±0.028、0.129±0.039비0.105±0.017、0.119±0.060비0.109±0.037],차이유통계학의의(P＜ 0.01혹＜0.05).량조24 hSBP、24 h DBP、dDBP、nSBP、nDBP、일간평균서장압변이계수、야간평균서장압변이계수비교차이무통계학의의(P＞0.05).결론 경동맥경화적노년원발성고혈압환자BPV명현고우비경동맥경화적노년원발성고혈압환자,BPV여경동맥IMT유일정적상관성.
Objective To observe blood pressure variability (BPV) in elderly patients with primary hypertension and carotid artery intima-media thickness (IMT),and analyze the correlation between BPV and atherosclerosis.Methods One hundred and nine patients with primary hypertension were divided into non-carotid atherosclerosis group (IMT ＜ 1.0 mm,49 cases) and carotid atherosclerosis group (IMT ≥ 1.0mm,60 cases).24 h ambulatory blood pressure monitoring (ABPM) was used to measure the 24-hour mean systolic blood pressure (24 h SBP),24-hour mean diastolic pressure (24 h DBP) ; SBP of daytime (dSBP)and nighttime (nSBP) ; DBP of daytime (dDBP) and nighttime (nDBP).And their standard deviation and coetficient of variation (CV) was calculated.Results dSBP,24 h SBPCV,24 h DBPCV,dSBPCV,nSBPCV in carotid atherosclerosis group was higher than that in non-carotid atherosclerosis group [(132.3 ± 12.1)mm Hg(1 mm Hg =0.133 kPa) vs.(122.7 ± 10.8) mm Hg,0.118±0.011 vs.0.107 ± 0.023,0.142 ± 0.058vs.0.116 ±0.028,0.129 ±0.039 vs.0.105 ±0.017,0.119 ±0.060 vs.0.109 ±0.037],and there was significant difference (P ＜ 0.01 or ＜ 0.05).There was no significant difference in 24 h SBP,24 h DBP,dDBP,nSBP,nDBP,dSBPCV,nSBPCV between two groups (P ＞0.05).Conclusions BPV of carotid atherosclerosis is higher than that of non-carotid atherosclerosis.BPV and carotid artery IMT has a certain relevance.
