CAJ | 학술논문

目的：分析甲状腺乳头状癌（PTC）合并桥本甲状腺炎（HT）的临床病理特点及预后。方法回顾性分析我院收治的68例PTC患者的临床特点、病理资料，其中合并HT患者29例，未合并HT患者39例。所有患者均接受药物和手术治疗，比较两组患者的临床和病理特点及预后情况。结果与未合并HT的PTC患者比较，合并HT的PTC患者女性比例明显较大，淋巴结转移明显减少（χ2＝4．41，4．04，P＜0．05）；两组患者在肿瘤病灶、包膜侵犯、甲状腺外侵犯、微小癌、多灶性肿瘤等方面差异均无统计学意义（P＞0．05）；随访期间，合并HT的PTC患者复发率10．3％，未合并HT的PTC患者复发率5．1％（χ2＝0．66，P ＞0．05）。结论 PTC合并HT好发于女性，淋巴结转移相对少，应常规行甲状腺全切加中央区颈部淋巴结清扫。
목적：분석갑상선유두상암（PTC）합병교본갑상선염（HT）적림상병리특점급예후。방법회고성분석아원수치적68례PTC환자적림상특점、병리자료，기중합병HT환자29례，미합병HT환자39례。소유환자균접수약물화수술치료，비교량조환자적림상화병리특점급예후정황。결과여미합병HT적PTC환자비교，합병HT적PTC환자녀성비례명현교대，림파결전이명현감소（χ2＝4．41，4．04，P＜0．05）；량조환자재종류병조、포막침범、갑상선외침범、미소암、다조성종류등방면차이균무통계학의의（P＞0．05）；수방기간，합병HT적PTC환자복발솔10．3％，미합병HT적PTC환자복발솔5．1％（χ2＝0．66，P ＞0．05）。결론 PTC합병HT호발우녀성，림파결전이상대소，응상규행갑상선전절가중앙구경부림파결청소。
Objective To analyze the clinical pathological features and prognosis of papillary thyroid carcinoma(PTC)with coexistent Hashimoto's thyroiditis(HT).Methods Clinical features and pathological data of 68 PTC patients who were treated in our hospital were retrospectively analyzed.There were 29 cases with co-existent HT(coexistence group)and 39 cases without HT(non-coexistence group).All the cases were given drugs and surgical treatment,the clinical-pathological features and prognosis were analyzed between the two groups.Result Compared with non-coexistence group,the ratio of female patients increased with decreased lymphatic metastasis in the coexistence group(χ2 =4.41,4.04,P<0.05).There were no significant differences on tumor lesions,capsular invasion,extrathyroidal extension,tiny thyroid carcinoma and multifocal tumor be-tween the two groups(P>0.05).The recurrence rates in coexistence group and non-coexistence group were 10. 3%and 5.1%(χ2 =0.66,P >0.05).Conclusion PTC with coexistent HT mainly occurs in women and it has a relatively low ratio of lymph node metastases.Thyroidectomy and lymph node dissection in the central neck area should be routinely performed.